Template:Side effects of combined androgen blockade with nilutamide and surgical castration
Appearance
Class | Side effect | Nilutamide 150 mg/day + orchiectomy (n = 225) (%)a,b |
Placebo + orchi- ectomy (n = 232) (%)a,b |
---|---|---|---|
Cardiovascular system | Hypertension | 5.3 | 2.6 |
Digestive system | Nausea | 9.8 | 6.0 |
Constipation | 7.1 | 3.9 | |
Endocrine system | Hot flashes | 28.4 | 22.4 |
Metabolic and nutritional system | Increased aspartate transaminase | 8.0 | 3.9 |
Increased alanine transaminase | 7.6 | 4.3 | |
Nervous system | Dizziness | 7.1 | 3.4 |
Respiratory system | Dyspnea | 6.2 | 7.3 |
Special senses | Impaired adaptation to darkness | 12.9 | 1.3 |
Abnormal vision | 6.7 | 1.7 | |
Urogenital system | Urinary tract infection | 8.0 | 9.1 |
Overall | 86 | 81 | |
Footnotes: a = Phase III studies of combined androgen blockade (nilutamide + orchiectomy) in men with advanced prostate cancer. b = Incidence ≥5% regardless of causality. Sources: [1] |
Template documentation
Usage
This template can be used to easily insert a table detailing the side effects of combined androgen blockade with nilutamide and surgical castration into an article. It comes with one pre-provided reference.
By passing the parameter |state=mw-collapsed
, the table can be displayed as collapsed by default.