Template:Relative affinities of noretynodrel, tibolone, and metabolites

Relative affinities (%) of noretynodrel, tibolone, and metabolites

Compound	Code name	PRTooltip Progesterone receptor	ARTooltip Androgen receptor	ERTooltip Estrogen receptor	GRTooltip Glucocorticoid receptor	MRTooltip Mineralocorticoid receptor	SHBGTooltip Sex hormone-binding globulin	CBGTooltip Corticosteroid binding globulin
Noretynodrel	–	6	0	2	0	0	0	0
Norethisterone (δ4-NYD)	–	67–75	15	0	0–1	0–3	16	0
3α-Hydroxynoretynodrel	–	?	?	?	?	?	?	?
3β-Hydroxynoretynodrel	–	?	?	?	?	?	?	?
Ethinylestradiol	–	15–25	1–3	112	1–3	<1	0.18	<0.1
Tibolone (7α-Me-NYD)	ORG-OD-14	6	6	1	?	?	?	?
Δ4-Tibolone	ORG-OM-38	90	35	1	0	2	1	0
3α-Hydroxytibolone	ORG-4094	0	3	4–6	0	?	?	?
3β-Hydroxytibolone	ORG-301260	0	4	3–29	0	?	?	?
7α-Methylethinylestradiol	–	?	?	?	?	?	?	?
Notes: Values are percentages (%). Reference ligands (100%) were promegestone for the PRTooltip progesterone receptor, metribolone for the ARTooltip androgen receptor, E2 for the ERTooltip estrogen receptor, DEXATooltip dexamethasone for the GRTooltip glucocorticoid receptor, aldosterone for the MRTooltip mineralocorticoid receptor, DHTTooltip dihydrotestosterone for SHBGTooltip sex hormone-binding globulin, and cortisol for CBGTooltip Corticosteroid-binding globulin. Sources:

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