Template:2001 NL Central standings
| Team | W | L | Pct. | GB | Home | Road |
|---|---|---|---|---|---|---|
| Houston Astros | 93 | 69 | .574 | — | 44–37 | 49–32 |
| St. Louis Cardinals | 93 | 69 | .574 | — | 54–28 | 39–41 |
| Chicago Cubs | 88 | 74 | .543 | 5 | 48–33 | 40–41 |
| Milwaukee Brewers | 68 | 94 | .420 | 25 | 36–45 | 32–49 |
| Cincinnati Reds | 66 | 96 | .407 | 27 | 27–54 | 39–42 |
| Pittsburgh Pirates | 62 | 100 | .383 | 31 | 38–43 | 24–57 |