Template:1945 American League standings
| Team | W | L | Pct. | GB | Home | Road |
|---|---|---|---|---|---|---|
| Detroit Tigers | 88 | 65 | .575 | — | 50–26 | 38–39 |
| Washington Senators | 87 | 67 | .565 | 1½ | 46–31 | 41–36 |
| St. Louis Browns | 81 | 70 | .536 | 6 | 47–27 | 34–43 |
| New York Yankees | 81 | 71 | .533 | 6½ | 48–28 | 33–43 |
| Cleveland Indians | 73 | 72 | .503 | 11 | 44–33 | 29–39 |
| Chicago White Sox | 71 | 78 | .477 | 15 | 44–29 | 27–49 |
| Boston Red Sox | 71 | 83 | .461 | 17½ | 42–35 | 29–48 |
| Philadelphia Athletics | 52 | 98 | .347 | 34½ | 39–35 | 13–63 |