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Tannishtha Reya

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Tannishtha Reya
Born
India
Alma materWilliams College
University of Pennsylvania

Tannishtha Reya is an Indian-born American cell and developmental biologist working in cancer research at Columbia University in New York. She has received numerous awards, including an NIH Director's Pioneer Award in 2009 and an NCI Outstanding Investigator Award in 2015.[1] Reya is particularly known for co-authoring an influential publication in 2001 coining the term "cancer stem cell" to describe a cancer cell that mirrors the properties of stem cells of healthy organs in the context of leukaemias or solid tumours.[2]

Education

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Reya was born in India and is the granddaughter of writers Buddhadeb Bose and Protiva Bose. She moved to the US when she was seventeen to take a liberal arts degree at Williams College in Massachusetts because she wanted to be "exposed to both literature and the sciences.".[3] She then pursued her PhD in immunology at the University of Pennsylvania under the guidance of Simon Carding. Reya conducted her postdoctoral research first in the laboratory of Rudolf Grosschedl at the University of California San Francisco and then with Irving Weissman at Stanford University.

Career

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Reya is professor of Physiology and Cellular Biophysics at Columbia University. Previously she was faculty at Duke University and the University of California, San Diego. Her research on acute myeloid leukaemia explored the possibilities of targeting a cell surface molecule (CD98) to inhibit the growth of cancer cells.[4] Her most recent research is in the field of pancreatic cancer.[5] She and her team are investigating the roles of immune system receptors and potential related therapies.[6][7]

Reya currently serves on the editorial board of the journal Science and has been the recipient of numerous grants, including Stand Up to Cancer grants in 2017 and 2019.[8][9] In 2019, Reya was interviewed by the Stem Cell Podcast.[10]

References

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  1. ^ "Tannishtha Reya | UCSD Profiles". profiles.ucsd.edu. Retrieved 2019-06-26.
  2. ^ Reya, Tannishtha; Morrison, Sean J.; Clarke, Michael F.; Weissman, Irving L. (November 2001). "Stem cells, cancer, and cancer stem cells" (PDF). Nature. 414 (6859): 105–111. Bibcode:2001Natur.414..105R. doi:10.1038/35102167. hdl:2027.42/62862. ISSN 0028-0836. PMID 11689955. S2CID 4343326.
  3. ^ Sedwick, Caitlin (2012-09-03). "Tannishtha Reya: Classic pathways, new views on cancer". The Journal of Cell Biology. 198 (5): 766–767. doi:10.1083/jcb.1985pi. ISSN 0021-9525. PMC 3432759. PMID 22945930.
  4. ^ Buschman, Heather (27 October 2016). "Antibody Breaks Leukemia's Hold, Providing New Therapeutic Approach". UC San Diego Health. Retrieved 2019-06-27.
  5. ^ Lytle, Nikki K.; Ferguson, L. Paige; Rajbhandari, Nirakar; Gilroy, Kathryn; Fox, Raymond G.; Deshpande, Anagha; Schürch, Christian M.; Hamilton, Michael; Robertson, Neil (April 2019). "A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma". Cell. 177 (3): 572–586.e22. doi:10.1016/j.cell.2019.03.010. PMC 6711371. PMID 30955884.
  6. ^ Sklar, Debbie L. (2019-04-04). "UCSD Researchers Find Inhibiting Hormone Receptor Could Stall Cancer Growth". Times of San Diego. Retrieved 2019-06-27.
  7. ^ Sisson, Paul (30 November 2018). "New center aims for pancreatic cancer prevention". medicalxpress.com. Retrieved 2019-06-27.
  8. ^ "Editorial Board | Science Signaling". stke.sciencemag.org. Retrieved 2019-06-26.
  9. ^ "'Dream Team' Including La Jollans Gets 'Stand Up to Cancer' $7M Grant". Times of San Diego. 2017-10-26. Retrieved 2019-06-26.
  10. ^ "Ep 144: "Multiscale Map of Stem Cell State in Pancreatic Adenocarcinoma" Featuring Dr. Tannishtha Reya". Stem Cell Podcast. 2019-06-11. Retrieved 2019-06-26.
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