Talk:Vesicular monoamine transporter

This is the talk page for discussing improvements to the Vesicular monoamine transporter article.
This is not a forum for general discussion of the article's subject.

Put new text under old text. Click here to start a new topic.
New to Wikipedia? Welcome! Learn to edit; get help.

Article policies

Find medical sources: Source guidelines · PubMed · Cochrane · DOAJ · Gale · OpenMD · ScienceDirect · Springer · Trip · Wiley · TWL

Medicine Low‑importance

	Medicine portal This article is within the scope of WikiProject Medicine, which recommends that medicine-related articles follow the Manual of Style for medicine-related articles and that biomedical information in any article use high-quality medical sources. Please visit the project page for details or ask questions at Wikipedia talk:WikiProject Medicine.MedicineWikipedia:WikiProject MedicineTemplate:WikiProject Medicinemedicine articles
Low	This article has been rated as Low-importance on the project's importance scale.

Molecular Biology: MCB

	This article is within the scope of WikiProject Molecular Biology, a collaborative effort to improve the coverage of Molecular Biology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Molecular BiologyWikipedia:WikiProject Molecular BiologyTemplate:WikiProject Molecular BiologyMolecular Biology articles
???	This article has not yet received a rating on the importance scale.
	This article is supported by the Molecular and Cell Biology task force (assessed as Low-importance).

Neuroscience Mid‑importance

	This article is within the scope of WikiProject Neuroscience, a collaborative effort to improve the coverage of Neuroscience on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.NeuroscienceWikipedia:WikiProject NeuroscienceTemplate:WikiProject Neuroscienceneuroscience articles
Mid	This article has been rated as Mid-importance on the project's importance scale.

Pharmacology Mid‑importance

	This article is within the scope of WikiProject Pharmacology, a collaborative effort to improve the coverage of Pharmacology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.PharmacologyWikipedia:WikiProject PharmacologyTemplate:WikiProject Pharmacologypharmacology articles
Mid	This article has been rated as Mid-importance on the project's importance scale.

VMAT1 in neurons?

I am looking up the literature on chromaffine cells and sympathetic neurons with respect to development and differences therein. The review Cell Tissue Res (2015) 359:333–341 DOI 10.1007/s00441-014-1947-0 by K.Huber (Segregation of neuronal and neuroendocrine differentiation in the sympathoadrenal lineage) enforces the notion the Vmat1 is only expressed in chromaffine cells and not in neurons and cites Weihe et al. Journal of Molecular Neuroscience 5(3): 149-164/$7.20 Localization of Vesicular Monoamine Transporter Isoforms (VMATI and VMAT2) to Endocrine Cells and Neurons in Rat. This is in contrast to the sentence: (Location:VMAT1:) It is also expressed in sympathetic neurons and blood platelets. I do not know where this comes from since it is lacking a reference. Please change it or add a citation. --B.Kleine (talk) 08:49, 5 October 2015 (UTC)[reply]

I have now got the paper by Brunk et al. It says just the opposite, VMat 2 is expressed in platelets. The paper cites a accessible reference for this: THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 278, No. 18, Issue of May 2, pp. 15850–15858, 2003; doi: 10.1074/jbc.M212816200. This is more consistent with latest review on chromaffin cells: Cell Tissue Res (2015) 359:333–341, DOI 10.1007/s00441-014-1947-0, which states that Vmat1 is restricted to chromaffin cells.--B.Kleine (talk) 03:45, 7 October 2015 (UTC)[reply]