Talk:Urticaria pigmentosa

note

I have urticaria pigmentosa. It gets worse in the summer and during the winter (when air pressure changes considerably). I've noticed that if I keep a constant comfortable body temperature, the problems seem to disappear. Also, my fingers and palms get swollen when I touch cold metal objects. I thought this was because of bacteria on doorknobs but I soon realized it was all kinds of metal, not just the doorknobs. So, from my experience, varying temperature can cause urticaria pigmentosa, as temperature stimulates the mast cells into producing histamine. This is worth mentioning.

Regarding this article, which seems to be pretty complete otherwise, I have a question. There is no known way of reducing the amount of mast cells in the body. My question is this: Shouldn't there be some other kind of treatment in which the cells are left alone but disabled, like a diet which limits their possibility of producing histamine or something similar?

I haven't been able to find anything about this anywhere. It would surely help a lot just knowing what chemical components (and the products that contain them) are used by these cells to produce the histamine. The article mentions nothing about that. It's also disappointing that most doctors don't know how to properly diagnose Urticaria pigmentosa. I once got tested for allergies (my mom thought I was allergic to aspirin) and the only allergen that my skin reacted to was histamine. The doctor thought that was normal and immediately discarded the possibility of my allergies being caused by histamine. No further tests were made to see if I had Urticaria pigmentosa, not even to confirm my mother's suspicions about it.