Talk:Trace amine-associated receptor

This is the talk page for discussing improvements to the Trace amine-associated receptor article.
This is not a forum for general discussion of the article's subject.

Put new text under old text. Click here to start a new topic.
New to Wikipedia? Welcome! Learn to edit; get help.

Article policies

Find medical sources: Source guidelines · PubMed · Cochrane · DOAJ · Gale · OpenMD · ScienceDirect · Springer · Trip · Wiley · TWL

Molecular Biology: MCB

	This article is within the scope of WikiProject Molecular Biology, a collaborative effort to improve the coverage of Molecular Biology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Molecular BiologyWikipedia:WikiProject Molecular BiologyTemplate:WikiProject Molecular BiologyMolecular Biology articles
???	This article has not yet received a rating on the importance scale.
	This article is supported by the Molecular and Cell Biology task force (assessed as High-importance).

Neuroscience High‑importance

	This article is within the scope of WikiProject Neuroscience, a collaborative effort to improve the coverage of Neuroscience on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.NeuroscienceWikipedia:WikiProject NeuroscienceTemplate:WikiProject Neuroscienceneuroscience articles
High	This article has been rated as High-importance on the project's importance scale.

Pharmacology Mid‑importance

	This article is within the scope of WikiProject Pharmacology, a collaborative effort to improve the coverage of Pharmacology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.PharmacologyWikipedia:WikiProject PharmacologyTemplate:WikiProject Pharmacologypharmacology articles
Mid	This article has been rated as Mid-importance on the project's importance scale.

Medicine Low‑importance

	Medicine portal This article is within the scope of WikiProject Medicine, which recommends that medicine-related articles follow the Manual of Style for medicine-related articles and that biomedical information in any article use high-quality medical sources. Please visit the project page for details or ask questions at Wikipedia talk:WikiProject Medicine.MedicineWikipedia:WikiProject MedicineTemplate:WikiProject Medicinemedicine articles
Low	This article has been rated as Low-importance on the project's importance scale.

Untitled

'

New review

It's probably worth using this review to add new content to phenethylamine, 3-iodothyronamine, trace amine, TAAR1, TAAR2, TAAR5, TAAR6, TAAR8, and this article. Seppi333 (Insert 2¢) 02:28, 4 February 2017 (UTC)[reply]

^[1]

References

^ Khan MZ, Nawaz W (October 2016). "The emerging roles of human trace amines and human trace amine-associated receptors (hTAARs) in central nervous system". Biomed. Pharmacother. 83: 439–449. doi:10.1016/j.biopha.2016.07.002. PMID 27424325.

Human trace amine-associated receptors

@Boghog: do you think the content within and layout of this table is suitable for covering these receptors in the article?

Also, do you think it's reasonable to just list "known/putative functions" and "known ligands" as well as explicitly state "other G protein coupling unknown" for these receptors when so few things are actually known about hTAAR2-hTAAR9? Seppi333 (Insert 2¢) 22:30, 15 May 2018 (UTC)[reply]

E.g., this review^[1] lists "CNS and periphery unknown" under the associated putative functions column in table 1 for all of these receptors, except for TAAR1. Off-topic: I emailed Dr. Berry and he was kind enough to multi-license figure 2 from this review so that I could upload it to Commons and use it in TAAR1. Seppi333 (Insert 2¢) 22:36, 15 May 2018 (UTC)[reply]

Hi Seppi333. The lack knowledge about what these receptor subtypes do is of course a direct consequence of a lack of selective ligands to probe their function. The way you have presented this in the table I think is fine. The only suggestion I have is to make clear which of the functions are known and which are putative. Also I found the pink color for pseudogenes distracting and unnecessary. It is clear enough from the text that these are pseudogenes. Boghog (talk) 05:03, 16 May 2018 (UTC)[reply]

Sounds good. Removing the coloring is fine with me. Thanks for the feedback! Seppi333 (Insert 2¢) 05:20, 16 May 2018 (UTC)[reply]

References

^ Berry MD, Gainetdinov RR, Hoener MC, Shahid M (December 2017). "Pharmacology of human trace amine-associated receptors: Therapeutic opportunities and challenges". Pharmacology & Therapeutics. 180: 161–180. doi:10.1016/j.pharmthera.2017.07.002. PMID 28723415.

[Human_trace_amines_and_hTAARs_October_2016_review-1] Khan MZ, Nawaz W (October 2016). "The emerging roles of human trace amines and human trace amine-associated receptors (hTAARs) in central nervous system". Biomed. Pharmacother. 83: 439–449. doi:10.1016/j.biopha.2016.07.002. PMID 27424325.

[Berry_hTAAR_pharmacology_December_2017_review-2] Berry MD, Gainetdinov RR, Hoener MC, Shahid M (December 2017). "Pharmacology of human trace amine-associated receptors: Therapeutic opportunities and challenges". Pharmacology & Therapeutics. 180: 161–180. doi:10.1016/j.pharmthera.2017.07.002. PMID 28723415.

[1]

[1]