Talk:Toxoplasmosis

Vaccination

Ok, after deeper consideration a vaccination information should be mentioned in this article here. Will add this under the "Research" section. Well, can I copy it (with little modification) from the Toxoplasma gondii article?

As of 2015, no approved human vaccine exists against Toxoplasmosis. Research on human Toxoplasma gondii vaccines is ongoing.

For sheep there is available an approved live vaccine called Toxovax (MSD Animal Health) which provides lifetime protection.

lion10 (talk) 19:06, 13. December 2015 (UTC)

References

Symptoms section needs to be rewritten to be about symptoms

It says:

Latent toxoplasmosis[edit] It is easy for a host to become infected with Toxoplasma gondii and develop toxoplasmosis without knowing it. In most immunocompetent people, the infection enters a latent phase, during which only bradyzoites are present,[16] forming cysts in nervous and muscle tissue. Most infants who are infected while in the womb have no symptoms at birth, but may develop symptoms later in life.[17]

When you read this, instead of telling you signs and symptoms, it tells you what the parasites are doing and the fact that babies infected in the womb can have no symptoms and might develop symptoms later on. The problem is that this section doesn't actually tell you any of the symptoms/signs, and it especially doesn't tell you symptoms/signs for someone who got the parasite while free from his womb.— Preceding unsigned comment added by 2604:4080:1106:0:51b5:f291:cec1:ec99 (talk) July 2014

Corrolations

" The prevalence of toxoplasmosis correlated with specific disease burden in particular countries explaining 23% of variability in disease burden in Europe. The analyses revealed that for example, DALY of 23 of 128 analyzed diseases and disease categories on the WHO list showed correlations (18 positive, 5 negative) with prevalence of toxoplasmosis and another 12 diseases showed positive trends (p<0.1). For several obtained significant correlations between the seroprevalence of toxoplasmosis and specific diseases/clinical entities, possible pathophysiological, biochemical and molecular explanations are presented."

• Toxoplasmosis – A Global Threat. Correlation of Latent Toxoplasmosis with Specific Disease Burden in a Set of 88 Countries https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963851/

In English

Current version Diagnosis of toxoplasmosis in humans is made by biological, serological, histological, or molecular methods, or by some combination of the above.[1] Toxoplasmosis can be difficult to distinguish from primary central nervous system lymphoma. It mimics several other infectious diseases so clinical signs are non-specific and are not sufficiently characteristic for a definite diagnosis. As a result, the possibility of an alternate diagnosis is supported by a failed trial of antimicrobial therapy (pyrimethamine, sulfadiazine, and folinic acid (USAN: leucovorin)), i.e., if the drugs produce no effect clinically and no improvement on repeat imaging.

The replacement I propose: Specialists use several methods to diagnose toxoplasmosis. It can be mistaken for a brain tumour, or other infectious diseases Because other illnesses have the same symptoms. Consequently, if the patient does not improve after administration of the usual medication (pyrimethamine, sulfadiazine, and folinic acid (called leucovorin in the US)), other illnesses should be considered.

I think this says the same thing in half as many words and clearer logic. However, it needs to be checked by a medical editor. I have flagged it accordingly. Humphrey Tribble (talk) 09:51, 15 May 2023 (UTC)