Talk:Totarol
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various problems
[edit]IUPAC name - Wouldn't that be 4b,5,6,7,8,8a,9,10-octahydro? Antimicrobial activity - Artemia & Caenorhabditis are not microorganisms. Biosynthesis - "defend themselves against antibacterial and antifungal organisms", "point of photosynthesis", & "oxidized at to form" do not make sense. Synthesis - 7 is not a Grignard. "finalized by treatment of with" does not make sense. Scheme 3 states that the product was (+-)-totarol but the text states (+)-totarol. Total enantioselective synthesis - The Wittig reaction between 11 & 12 did not form any rings and was not a cyclization. Typos - achieved with complete sterEoselectivity & totarane diAStereomers There does not appear to have been any rearrangement going from 17 to 18. Scheme 4 - what is PH3P in 12? Total chemoenzymatic synthesis - treatment of 20 with HCl & TsOH should not produce the opposite enantiomer as shown in Scheme 6. 69.72.92.144 (talk) 05:40, 15 October 2014 (UTC)