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Talk:Tesofensine

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Added some data to the drug box. Data taken from the following article, and references therein: Bilz0r (talk) 09:05, 23 October 2008 (UTC)[reply]

Lehr T, Staab A, Tillmann C; et al. (2007). "Population pharmacokinetic modelling of NS2330 (tesofensine) and its major metabolite in patients with Alzheimer's disease". British journal of clinical pharmacology. 64 (1): 36–48. doi:10.1111/j.1365-2125.2007.02855.x. PMC 2000606. PMID 17324246. {{cite journal}}: Explicit use of et al. in: |author= (help); Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link) 

Check the PubChem structure linked to this article. Absolutely incorrect.--ChemSpiderMan (talk) 16:55, 20 December 2007 (UTC)[reply]

Removed. -- Ed (Edgar181) 16:14, 21 December 2007 (UTC)[reply]

Cocaine

[edit]

Tesofensine and cocaine have very similar structures and inhibit reuptake of the same three neurotransmitters. We should sniff out some sourced commentary about this... Wnt (talk) 18:19, 13 January 2009 (UTC)[reply]

Yeah, no kidding. It looks exactly like someone familiar with the differences between zoloft and tametraline decided to make a more serotonergic version of troparil, then decided while they were wiping out vulnerable ester linkages they'd go ahead and make the other one into the ether version of cocaethylene. 100% recycled subgroups from other drugs here. Zaphraud (talk) 00:47, 12 May 2009 (UTC)[reply]