Talk:T-cell receptor

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Molecular Biology: MCB

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I replaced the image of the TCR complex with a higher resolution image that does not include a specific coreceptor, as both CD4+ and CD8+ T cells express the TCR complex. Anriar (talk) 03:58, 20 February 2010 (UTC)== Redirects or articles? ==[reply]

Should αβ T cells and αβ T cell receptors redirect to this page, or should they have their own articles, as for γδ T cells and γδ T cell receptors? LeadSongDog come howl! 16:07, 15 September 2010 (UTC)[reply]

"... many TCR recognize the same antigen and many antigens are recognized by the same TCR." This statement *seriously* needs a reference. Srigita (talk) 23:39, 22 August 2012 (UTC)[reply]

"...whereas the variable region of the β-chain has an additional area of hypervariability (HV4) that does not normally contact antigen and, therefore, is not considered a CDR ." <--- is this necessary??Srigita (talk) 00:58, 23 August 2012 (UTC)[reply]

One issue I have with the overall manner in which the page is written, is that the heading is TCR, but describes antigen recognition within the MHC complex - and g/d are thought to not require MHC. So, I'm wondering if the structure of the article should have a general TCR definition, followed by sections for a:b and g:d, or if it should simply be included that we're talking about a:bTCR for the most part.Srigita (talk) 01:03, 23 August 2012 (UTC)[reply]

The section on Generation of TCR should include information from the following (sorry, I don't have time right now): http://www.ncbi.nlm.nih.gov/books/NBK27145/figure/A460/?report=objectonly http://www.ncbi.nlm.nih.gov/books/NBK27145/figure/A461/?report=objectonly Srigita (talk) 02:09, 23 August 2012 (UTC)[reply]

When I view the image of the TCR binding the right most "g" is cut off, spelling out, "antigen presentin cell", a typo caused by the cutoff (the g is there, but just off the edge) — Preceding unsigned comment added by Leedmcdaniel (talk • contribs) 16:53, 17 December 2012 (UTC)[reply]