Talk:Sulfonylurea

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Glimepiride

Glimepiride is not 3rd generation sulfonylurea. It is a second generation sulfonylurea. The article is incorrect.

^[1] "Pharmacokinetics — Glipizide, glyburide (glibenclamide), gliclazide, and glimepiride are so-called second-generation sulfonylureas."
^[2] "Chemical Class: 2nd Generation Sulfonylurea"
^[3] "...second-generation drugs: glimepiride, glipizide, and glyburide (Table 83–11)."

Vana3474 (talk) 22:18, 26 February 2012 (UTC)[reply]

The current version of glimepiride states that some classify it as a second- and some as a third-generation sulfonylurea. This textbook, for instance, does the latter. Perhaps we should mention both views. JFW | T@lk 22:44, 26 February 2012 (UTC)[reply]

I have made an edit[1] that states both opinions. JFW | T@lk 10:51, 27 February 2012 (UTC)[reply]

References

^ Sulfonylureas and meglitinides in the treatment of diabetes mellitus. UpToDate [Internet database]. Wolters Kluwer Health, Inc. 2011 [cited 2011 Feb 26]. Available from: http://www.uptodate.com with subscription.
^ Glimepiride. Micromedex® Healthcare Series [Internet database]. Greenwood Village, Colo: Thomson Reuters (Healthcare) Inc. [cited 2011 Feb 26]. Available from: http://www.thomsonhc.com with subscription.
^ Triplitt CL, Reasner CA. Chapter 83. Diabetes Mellitus. In: DiPiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM, eds. Pharmacotherapy: A Pathophysiologic Approach. 8th ed. New York: McGraw-Hill; 2011. http://www.accesspharmacy.com/content.aspx?aID=7990956. Accessed February 26, 2012.

Pesticides

Agree that this is an important group of agrochemicals, but think the two topics are too different from each other to belong in one article. Suggest to rename this article "Sulfonylurea antdiabetic medications" and create a new article "Sulfonylurea herbicides" Formerly 98 (talk) 19:27, 4 January 2015 (UTC)[reply]

Agreed that the two topics deserve separate articles, but we should first determine what the primary topic is. Google searches generated the following statistics:

sulfonylurea+herbicides – 89,300 results
sulfonylurea+diabetes – 426,000 results

Hence one could argue that "antidiabetic sulfonurea" is the primary topic and we should leave this article unchanged add add a hatnote with a link to a new sulfonylurea herbicides article. Boghog (talk) 19:47, 4 January 2015 (UTC)[reply]

Thanks for coming to the rescue on my hasty insertion to raise the issue of a whole other class of molecules with bioactivity. I will probably move my list of the place suggested by Boghog and then add some sort of link for those looking for agrichemical info. --Smokefoot (talk) 20:25, 4 January 2015 (UTC)[reply]

Update

crossposted at talk:herbicide

I came to this page with a similar request:

Products such as "Flazasulfuron" are used for weed control and as ground-clear herbicides. Our article Herbicide doesn't point to Sulfonylurea in this context and our articles on Sulfonylureas don't reference their use as herbicides. It's also unclear which names are product vs. chemical names. Could someone improve coverage in this area so that

Herbicidal properties of these compounds are noted in their relevant articles, and in our articles Sulfonylurea and Flazasulfuron (which doesn't seem to exist);
Flazasulfuron is listed under relevant herbicidal articles as it seems to be a common kind of total herbicide.

Not sure what we need to say in this area. FT2 ^{(Talk | email)} 12:59, 20 December 2015 (UTC)[reply]

Thank you for pointing out the omission. Flazasulfuron has been created and the sulfonylurea article has been modified to acknowledge this class of herbicides.--Smokefoot (talk) 15:58, 20 December 2015 (UTC)[reply]

Rubecuber (talk) 15:29, 22 January 2018 (UTC)[reply]

[1] Sulfonylureas and meglitinides in the treatment of diabetes mellitus. UpToDate [Internet database]. Wolters Kluwer Health, Inc. 2011 [cited 2011 Feb 26]. Available from: http://www.uptodate.com with subscription.

[2] Glimepiride. Micromedex® Healthcare Series [Internet database]. Greenwood Village, Colo: Thomson Reuters (Healthcare) Inc. [cited 2011 Feb 26]. Available from: http://www.thomsonhc.com with subscription.

[3] Triplitt CL, Reasner CA. Chapter 83. Diabetes Mellitus. In: DiPiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM, eds. Pharmacotherapy: A Pathophysiologic Approach. 8th ed. New York: McGraw-Hill; 2011. http://www.accesspharmacy.com/content.aspx?aID=7990956. Accessed February 26, 2012.

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