Talk:Sulfanilamide
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Domagk and Trefouël
[edit]“Gerhard Domagk and Jacques and Therese Trefouel (1935) are generally credited with the discovery of sulfanilamide”
This sentence makes a confusion between discovery of Prontosil (sulfamidochrysoïdine), by German chemist Domagk at the beginning of year 1935, and later discovery, at the end of the same year, of sulfanilamide (p-aminophénylsulfamide), by French team Jacques and Thérèse Tréfouël, Federico Nitti and Daniel Bovet, in laboratory of Ernest Fourneau at Pasteur Institute. Le sulfamide or 1162 F (F as the first letter of Fourneau) is a metabolic part of Prontosil, the only one effective against bacteria. Sulfamidothérapie really began when this active agent had been isolated at Pasteur Institute.
I am myself not able to contribute in such bad English you can read here, so I pray you to mention the fact. You may refer to your page Sulfonamide (medicine) or Sulfa drug and to French articles fr:Ernest Fourneau, fr:Gerhard Domagk, fr:Antibiotique sulfamidé, fr:Daniel Bovet, fr:Prontosil, fr:Institut Pasteur. Regards. --Thierry (talk) 09:22, 28 April 2010 (UTC)
IUPAC Name
[edit]ChemSpider lists 4-[(E)-(4-aminophenyl)diazenyl]benzenesulfonamide as the IUPAC systematic name, but this is clearly wrong (just saying). Most sources list 4-aminobenzenesulfonamide as the IUPAC name but this does not properly reflect how the sulfamoyl group is connected to the aniline. I think that 4-aminobenzene-S-sulfonamide would be better. Regards, Simon de Danser (talk) 06:28, 21 November 2020 (UTC)