Talk:Shai Efrati

Feedback from New Page Review process

I left the following feedback for the creator/future reviewers while reviewing this article: Thank you for this new article. Note that it is currently an "orphan" meaning that no other Wikipedia articles link TO it. This makes the article tough to find for interested readers. For pointers, follows the links in the notice at the top of the article..

---DOOMSDAYER520 (Talk|Contribs) 18:00, 8 October 2019 (UTC)

Proposing article for deletion

Efrati founded and currently runs one of the two Hyperbaric chamber in Israel, which is among the biggest ones in the world. he runs a vast research in the hyperbaric field as the Institute Director in addition to his role as the Head of Research and Development unit at Yitzhak Shamir Medical Center. His researches, both in hyperbaric and general medicine received significant attention from independent sources. I just added a phrase about his research in the field of fibromyalgia and a source about the significance of the HBOT in Israel and the significance of Sagol Center for Hyperbaric Medicine In hebrew. These are the reasons it meets the criteria of notability. Naftalig (talk) 12:50, 3 November 2019 (UTC)

HBOT and hyperoxia hypoxia paradox

In the United States and other places HBOT is placing a person and 100% Oxygen environment and increasing pressure to two to two and a half times atmospheric pressure. The oxygen saturation has various documented effects including aiding healing and many others.

Dr Efrati and his team are exploiting a different phenomenon called hyperoxia hypoxia paradox. When the human body goes into hypoxia (oxygen starvation for lack of a better definition) the body briefly responds by producing a number of effects including generating a number of specialized cells including apparently several types of stem cells apparently in an effort to counteract the effects of hypoxia. This is a very brief process and occurs right before the beginning process of death that hypoxia causes. You cannot use hypoxia to study this effect in humans because you can damage the human body.

The process doctor Efrati and his colleagues use is different from standard HBOT therapy. When the human body is in a high-pressure environment two to three times normal atmospheric pressure and a person breaths pure oxygen, the tissues in the body become hyper saturated with oxygen (like normal HBOT in many countries). Dr. Efrati and his colleagues have their patients breathe pure oxygen for 15 to 20 minutes and then they take off the oxygen mask which switches the person to normal oxygen mix (approximately 20% that exist in Earth's atmosphere that we breathe every day). This is still at several times normal pressure. Because the tissues are hyper oxygenated they start losing the oxygen to go back to a normal saturation level. This reduction in oxygenation (going back to "normal") triggers the hypoxia reaction in human bodies without the danger that normal hypoxia causes. Because the reduction of oxygen starts when the body is hyper saturated with oxygen, this triggering of hypoxia reaction causes no damage to the body but triggers all the cell production that hypoxia produces. This process is called the hyperoxia hypoxia paradox. This is a very subtle process and people have to go through many cycles for weeks at a time to produce the effects that Dr. Efrati and his colleagues are documenting. 2600:1700:FDE0:A470:DC99:1898:2098:1771 (talk) 06:41, 22 June 2022 (UTC)