Talk:Reed–Sternberg cell

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"The presence of these cells is pathognomonic in the diagnosis of Hodgkin's lymphoma. They can also be found in reactive lymphadenopathy (such as infectious mononucleosis, carbamazepine associated lymphadenopathy) and rarely non-Hodgkin lymphomas."

If these cells can be found in conditions other than HL, how are they pathognomonic for HL? —Preceding unsigned comment added by 75.180.47.86 (talk) 23:47, 6 May 2010 (UTC)[reply]

The Role of EBV

"Reed-Sternberg cells (also known as lacunar histiocytes for certain types) are different giant cells found with light microscopy in biopsies from individuals with Hodgkin's lymphoma (aka Hodgkin's disease; a type of lymphoma) primarily due to EBV..."

I am having trouble understanding how EBV fits into the sentence. Is EBV known to be a primary cause of the generation of Reed Sternberg cells? I think a reference would be helpful.

Aal42 (talk) 21:29, 8 March 2011 (UTC)[reply]