Talk:Phloretin

Phloretin is not Naringenin chalcone

Phloretin and Naringenin chalcone are two different chemicals.

Naringenin chalcone: http://www.agrool.gr/files/naringenin%20chalcone.jpg

Naringenin chalcone has a doublebond.

Sorry for my bad english.

Kind regards, Threonin. — Preceding unsigned comment added by Threonin (talk • contribs) 11:00, 11 January 2011 (UTC)[reply]

Phloretin is a reversible inhibitor. Phloretin inhibits urea transport in toads, with increased Phloretin concentration urea transport is inhibited, however once Phloretin is removed the urea is able to move. ^[1]

Phloretin also inhibits glucose transport and Protein Kinase C, which induces apoptosis (cell death). ^[2]

Phloretin induces cell cycle arrest and inhibits cell proliferation. Phloretin can be used as a therapeutic effect for tumours as seen in Glioblastoma. ^[3]

Arzo12 (talk) 22:26, 7 October 2016 (UTC)Arzo[reply]

References

[1] ttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC302408/pdf/jcinvest00182-0145.pdf

[2] ttp://journals2.scholarsportal.info/pdf/03043835/v119i0002/207_paibm4biogtt.xml

[3] ttp://download.springer.com/static/pdf/628/art%253A10.1007%252Fs11060-016-2107-z.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs11060-016-2107-z&token2=exp=1475875973~acl=%2Fstatic%2Fpdf%2F628%2Fart%25253A10.1007%25252Fs11060-016-2107-z.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs11060-016-2107-z*~hmac=dd946bc04e8423a335dd96e4698a8b91c6812ed49748f1decf95dc14531f15ae

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