Talk:Pattern recognition receptor
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Xa21
[edit]The paper reporting the bacterial ligand of Xa21 was retracted and is currently under re-investigation. I made some edits to reflect that in 'Plant PRRs'. — Preceding unsigned comment added by 149.155.221.31 (talk) 22:32, 2 December 2014 (UTC)
Mannose receptor
[edit]I added a lot of detail about the serine cascade. Hopefully not too much for the scope of the article. Sjodenenator (talk) 04:28, 9 March 2010 (UTC)
PAMPs
[edit]To avoid getting into an edit war, I'd like to ask for the view of other editors on the subject of PAMPs. It seems that one editor opposes the use of pathogen-associated molecular patterns (or PAMPs) in this article (and in the Toll-like receptor page) and wishes to replace this expression with microbial-associated molecular patterns (MAMPs). My view is that the PAMPs term is widely used in existing literature and is currently the accepted terminology for ligands of TLRs, so it should not be completely removed from this page or the TLR page. At the moment there is little reference to MAMPs, (in fact I did find 2 very recent articles referring to these,[1][2] but no other references) so to avoid confusion, I agree this term could be introduced here, but not at the complete exclusion of PAMPs. Could other people please leave their comments on this? Ciar 03:39, 26 February 2007 (UTC)
- ^ Mackey D, McFall A (2006). "MAMPs and MIMPs: proposed classifications for inducers of innate immunity". Mol Microbiol. 61 (6): 1365–71. PMID 16899081.
- ^ Swerdlow M, Kennedy D, Kennedy J, Washabau R, Henthorn P, Moore P, Carding S, Felsburg P (2006). "Expression and function of TLR2, TLR4, and Nod2 in primary canine colonic epithelial cells". Vet Immunol Immunopathol. 114 (3–4): 313–9. PMID 17027090.
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- current usage should be used in Wikipedia. Wikipedia is not a battlefield for warring academics over linguistics and terminology.--ZayZayEM 06:31, 5 March 2007 (UTC)
- I agree with the two above posts - the abbreviation "PAMP" is used in a very large portion of recently published articles. Certainly this page should mention/clarify some of the other abbreviations. My lab uses PAMPs and MEMS (microbe expressed molecular structures) interchangeably in conversation. Of course there are some very strong opinions/arguments over which term is most appropriate (I've heard the argument that these aren't limited to "pathogens" a million times). Maybe one of these terms will win out after a few years. For now, this page should include all abbreviations that are currently in use.
--Matthaller (talk) 20:08, 19 May 2008 (UTC)
- Definitely introduce both.Sjodenenator (talk) 04:28, 9 March 2010 (UTC)
Wiki Education assignment: Biochemistry I
[edit]This article was the subject of a Wiki Education Foundation-supported course assignment, between 24 January 2023 and 11 May 2023. Further details are available on the course page. Student editor(s): Ghardy25 (article contribs).
— Assignment last updated by Ghardy25 (talk) 16:07, 21 March 2023 (UTC)