Talk:Papain

This article is within the scope of WikiProject Food and drink, a collaborative effort to improve the coverage of food and drink related articles on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Food and drinkWikipedia:WikiProject Food and drinkTemplate:WikiProject Food and drinkFood and drink articles

Low

This article has been rated as Low-importance on the project's importance scale.

Food and Drink task list:

To edit this page, select here

Here are some tasks you can do for WikiProject Food and drink:

Help bring these Top Importance articles currently B Status or below up to GA status: Agaricus bisporus (i.e. mushroom), Beef, Bread, Curry, Drink, Food, Ham and eggs, Soy sauce, Sushi, Yogurt
Bring these Top Importance articles currently at GA status up to FA status: Beer, French cuisine, Sugar
Bring these High Importance articles currently at GA status up to FA status: Apple, Burger King, Fish
Participate in project-related deletion discussions.
Delete unrelated trivia sections found in articles. Please review WP:Trivia and WP:Handling trivia to learn how to do this.
Add the {{WikiProject Food and drink}} project banner to food and drink related articles and content to help bring them to the attention of members. For a complete list of banners for WikiProject Food and drink and its child projects, select here.
Provide photographs and images for Category:Wikipedia requested images of food
Consider joining this project's Assessment task force. List any project ideas in this section

Note: These lists are transcluded from the project's tasks pages.

Molecular Biology: MCB Low‑importance

	This article is within the scope of WikiProject Molecular Biology, a collaborative effort to improve the coverage of Molecular Biology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Molecular BiologyWikipedia:WikiProject Molecular BiologyTemplate:WikiProject Molecular BiologyMolecular Biology articles
Low	This article has been rated as Low-importance on the importance scale.
	This article is supported by the Molecular and Cell Biology task force (assessed as Mid-importance).

Alternative medicine

This article is within the scope of WikiProject Alternative medicine, a collaborative effort to improve the coverage of Alternative medicine related articles on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Alternative medicineWikipedia:WikiProject Alternative medicineTemplate:WikiProject Alternative medicineAlternative medicine articles

Dietary Supplements Low‑importance

	Papain is part of WikiProject Dietary Supplements, a collaborative attempt at improving the coverage of topics related to dietary supplements. If you would like to participate, you can choose to edit this article, or visit the project page for more information.Dietary SupplementsWikipedia:WikiProject Dietary SupplementsTemplate:WikiProject Dietary SupplementsDietary supplement articles
Low	This article has been rated as Low-importance on the project's importance scale.

Pharmacology Low‑importance

	This article is within the scope of WikiProject Pharmacology, a collaborative effort to improve the coverage of Pharmacology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.PharmacologyWikipedia:WikiProject PharmacologyTemplate:WikiProject Pharmacologypharmacology articles
Low	This article has been rated as Low-importance on the project's importance scale.

Not a catalytic triad based enzyme!

Papain hasn't got a catalytic triad action mechanism but, actually, a catalytic diad (if we can call this so). In fact the active aminoacid (Cys25) is "helped" only by the next-standing His159, which induce the deprotonation of Cys25 -SH, to make it more reactive. But residue 158 isn't Asn (it is Asp) and it can't participate to the action mechanism because it isn't in the right position (it is oriented in the wrong direction). Catalytic triad based mechanisms are mostly used in Ser-proteinases, while -SH group in tiol-proteinases like papain is nucleofilic enough to work with the presence of the sole His residue. —Preceding unsigned comment added by Cigo86 (talk • contribs) 11:44, 10 December 2007 (UTC)[reply]

WikiProject Food and drink Tagging

This article talk page was automatically added with {{WikiProject Food and drink}} banner as it falls under Category:Food or one of its subcategories. If you find this addition an error, Kindly undo the changes and update the inappropriate categories if needed. The bot was instructed to tagg these articles upon consenus from WikiProject Food and drink. You can find the related request for tagging here . Maximum and carefull attention was done to avoid any wrongly tagging any categories , but mistakes may happen... If you have concerns , please inform on the project talk page -- TinucherianBot (talk) 17:43, 3 July 2008 (UTC)[reply]

Quote from FDA announcement

It is not clear whether the FDA-quote under 'Action by the FDA to restrict marketing of all topical drug products containing papain' (which btw is a far too long subtitle in my opinion) encomprises the rest of the section or only one or two (or three) of the following paragraphs. Also, a reference to the FDA-announcement in question MUST BE ADDED to be in accordance with wiki-guidelines on referencing! Larsenbagvendt (talk) 13:18, 26 March 2009 (UTC)[reply]

Hi. Although I'm not the one who did the original edit, I'm quite new to Wikipedia so I don't know how to add references; So if anyone can please take these sources and add them I'd be very happy (or supply a link on how it's done and I'll be happy to learn)

http://www.highbeam.com/doc/1G1-188489762.html
http://www.fda.gov/OHRMS/DOCKETS/98fr/FDA-2008-N-0481-n.pdf

Cheers everyone :D - Squaredevil (talk) 16:45, 5 April 2009 (UTC)[reply]

Ok nevermind, I figured it out. I only edited the first two sentence of the paragraph; I have no idea about the rest of it, the sources cited (but with no ref) and the 'facts' stated. - Squaredevil (talk) 17:03, 5 April 2009 (UTC)[reply]

That whole section was copied and pasted from an FDA press release. Now, I'm told that fda.gov is in the public domain, so that's alright, but the original document is a press release so some work is still needed to wikify. Sorry again for the ugly template earlier, but sometimes it's what you need to attract the attention (for want of better words) of more well-informed editors. I intend to fix it, but then again I intend to fix a lot of things. Tomásdearg92 (talk) 01:48, 4 February 2014 (UTC)[reply]

Another use

Anecdotally, papain (from the latex of an unripe papaya fruit) can be used to remove sea urchin spines stuck under the skin, possibly by breaking their structure down — Preceding unsigned comment added by 114.121.239.81 (talk) 17:04, 9 December 2016 (UTC)[reply]