Talk:Mycoestrogen

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Problematic claims

The article claims “Zearalenone is the main phyto-oestrogen consumed in the USA.” citing Kuiper-Goodman (1990). The claim is not at all supported by the cited source.

With regard to zearalenone and cancer, the article cites a single research paper and states: “It may be one dietary factor that can reduce the prevalence of breast cancer.” It does not acknowledge that this inference was based on a single study, or that the results pertained to rats. Although the finding is similar to that of Nikaido et al. (2003), the Wikipedia statement does not acknowledge dissimilar results, e.g. a study by Belli et al. finding that late-fetal or neonatal administration of zearalenone to rats resulted in increased incidence of hyperplasia of mammary tissue, and it does not acknowledge other studies indicating carcinogenicity of zearalenone, e.g. Ahamed et al. (2001), Makela et al. (1994), Dees et al. (1997), National Toxicology Program (1982), among others. Claims on such matters should be based on scholarly review, rather than on an individual study. Caution is needed when generalizing from research on a single species. Also, because dosages in some research trials may be quite high relative to normal dietary intake, caution is needed when using such trials as a basis for inferring effects of dietary intake. Schafhirt (talk) 19:55, 1 August 2015 (UTC)[reply]

No explanation of the purpose of mycoestrogens?

I'm somewhat baffled by this. The article outlines the use of mycoestrogens by humans, how its metabolized and what health effects it has. It doesn't at any point actually explain why some fungi produce it and what biological role it plays. 109.76.87.125 (talk) 00:29, 27 May 2020 (UTC)[reply]