Talk:Mycobacterium avium intracellulare
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Species name "avium" is obsolete for M. intracellulare
[edit]The correct name is just Mycobacterium intracellulare, and in the past decade is usually referred to that way in scientific literature, unless referring to a complex of species, not a subspecies.
M. intracellulare has been determined to be a separate species by genetic methods; "M. avium and M. intracellulare are two species, but some serotypes, now designated M. intracellulare, actually belong to M. avium." [1] "M. avium and M. intracellulare are difficult to distinguish by means of biochemical tests and by means of numerical taxonomy. DNA-DNA hybridization confirms that these species are different but indicates that some serovars of M. intracellulare actually belong to the species M.avium..." [2] Those genetic findings are buttressed by proteomic similarity between M. a. avium and another M. a. subspecies, a similarity lacking between that subspecies and M. intracellulare; "Rabbit antisera were raised to some of the strains [of M. avium paratuberculosis;] All were found to be antigenically identical with M. avium and none were found to belong to M. intracellulare." [3].
Also note the proposed species name used by Mycobacterium avium Complex disease listing information from the Center for Disease Control.
C4dn (talk) 18:38, 7 January 2010 (UTC)
Journal articles in the past ten years do use the phrase "Mycobacterium avium-intracellulare", but they usually seem to be refering to a complex of related species, not referring to M. intracellulare as a subspecies of M. avium; for example: "This polyvalent antiserum contains antibodies to serotypes 1, 2,3 and 18 of the M. avium-intracellulare-scrofulaceum complex of organisms" [4] The hyphen is an indication that the authors do not mean the phrase to refer to a subspecies of M. avium. C4dn (talk) 17:52, 9 January 2010 (UTC)
References
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Baess, I (1979). "Deoxyribonucleic acid relatedness among species of slowly-growing mycobacteria". Acta Pathol Microbiol Scand B. 87 (4): 221-226. PMID 115225.
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Baess, I (1983). "Deoxyribonucleic acid relationships between different serovars of Mycobacterium avium, Mycobacterium intracellulare and Mycobacterium scrofulaceum". Acta Pathol Microbiol Scand B. 91 (3): 201-203. PMID 6880745.
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McIntyre, G; Stanford, JL (1986). "Immunodiffusion analysis shows that Mycobacterium paratuberculosis and other mycobactin-dependent mycobacteria are variants of Mycobacterium avium". J Appl Bacteriol. 61 (4): 295-298. PMID 3096932.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ Collins, P (1983). "THE PATHOGENICITY OF MYCOBACTERIUM AVIUM AND RELATED MYCOBACTERIA FOR EXPERIMENTAL ANIMALS": 27-35. PMID 6337261.
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