Talk:Metamizole
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discrepancies between legal status on map and in the text
[edit]India: 'over the counter' on the map versus 'approval withdrawn in 1973' in words. Lodidol (talk) 09:36, 18 November 2016 (UTC)
Sodium salt vs acid form
[edit]The two different styles of images in the infobox are not consistent with one another. File:Metamizole2DACS.svg is the sulfonic acid whereas File:Metamizole ball-and-stick.png is the sodium sulfonate. Most of the external links seem to point to the sulfonic acid, or have the sodium salt but call it "metamizole sodium" (or related terminology). So is "metamizole" itself the sulfonic acid form, and the sodium salt one specific preparation? DMacks (talk) 04:54, 25 September 2017 (UTC)
Map should be changed
[edit]use map: Crimea is Ukraine and should be considered as subordinated to the Ukrainian law. 83.253.222.108 (talk) 17:51, 16 October 2022 (UTC)
- Noticed the same discrepancy about Crimea, still marked as russian territory. Moreover, Crimea isn't shown as russia in the previous map that the current one is based on, so this change has apparently been introduced by the current map author. 77.85.6.55 (talk) 16:39, 16 July 2023 (UTC)
- I used the blank copy of the BlankMap-World.svg map, that map has Crimea under Russia, there is a discussion in the blank copy at: c:File_talk:BlankMap-World.svg#Russia-Ukraine_update, but even if it coded in that way, it still enables to color Crimea differently than Russia and Ukraine, in case the drug has different availability in that region. If it is over-the-counter (OTC) in Ukraine, there would be no dispute, as they would all be light blue, but I need a source/reference of that information. I do think it is OTC, specially in times of war, but I need a reference to back it up. -- Arthurfragoso (talk) 02:27, 19 July 2023 (UTC)
Analgin Trademark
[edit]I noticed the most common trademarks are Novalgin in the west (Latin America and western Europe), held by Sanofi. And Analgin (анальгин) in Slavic and Asian countries (China and India), except Japan and Korea that calls it Sulpyrine.
I was curious about the Analgin trademark, but its complex. The Bulgarian pharmaceutical Sopharma holds the trademark in the following countries:
- Analgin [1]
- Kyrgyzstan, Latvia, Mongolia, Vietnam, Georgia, Turkmenistan, Azerbaijan, Bosnia and Herzegovina, Belarus, Croatia, Hungary, Kazakhstan, Moldova, Montenegro, Poland, Romania, Tajikistan, Ukraine
- Analgin Sopharma [2]
- Estonia, Georgia, Greece, Lithuania, Türkiye, Armenia, Azerbaijan, Bosnia and Herzegovina, Croatia, Hungary, Latvia, Moldova, Montenegro, Republic of North Macedonia, Mongolia, Romania, Tajikistan, Vietnam
In an interview, Sopharma CEO said: [3]
In some countries Analgin® is a protected trademark. According to the Russian pharmacopoeia, Analgin® is /…./
But it is cut out, and not knowing the Russian language, its difficult to find out. It seems to be a public non trademarkable name, but I don't know.
In Russia, there is a "анальгин анальгинультра анальгин - ультра" (analgin analginultra analgin - ultra) trademark for Оболенское (Obolenskoe Pharmaceutical Enterprise) but that is not the same as just "analgin", idk, can anyone confirm?
I also found out another major producer under the Analgin brand is the Borimed from Belarus. They provide pills to: [4] - Belarus, Azerbaijan, Kazakhstan, Kyrgyzstan, Russian Federation, Turkmenistan, Uzbekistan.
And injection form to: [5] - Belarus, Azerbaijan, Armenia, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russian Federation, Uzbekistan.
As Sopharma also holds the Trademark in Belarus, maybe Borimed pays licensing fees to Sopharma. (at least before the current war)
In India, the official documents refer to this drug as Analgin. [6] Makes me wonder why.
-- Arthurfragoso (talk) 23:01, 11 August 2023 (UTC)
Analgin
Synonyms: Alginodia, Algopyrine, Aminopyrine Sodium Sulfonate, Bonpyrin, Cibalgin, Dipyrone, Metamizolum, Methampyrone, Narone, Nartate, Neomelubrin, Novaldin, Novalgin, Novaminosulfon, Novemina, Paralgin, Pydirone, Sulpyrin.
Methanesulfonic acid, (antipyrinylmethylamino)-, sodium salt C13H17N3O4S.Na
Analgesic and antipyretic drug.
Mashkovskii, M. D. Lekarstvennye sredstva, 1958. p. 62. Merck index, 1960. p. 385.
— Russian drug index, page 92. [7]
— Arthurfragoso (talk) 01:47, 12 August 2023 (UTC)
Searching for "анальгин" (Analgin) in Ministry of Health of the Russian Federation - Unified Structured Directory-catalog of Medicines brings:
МНН: Метамизол натрия (INN: Metamizole sodium)
Торговое наименование (Trade name): Анальгин (Analgin)
And it lists a bunch of pharmaceutical companies using the brand name Analgin.
I also found this article claiming Analgin to be a public trademarks:
The Ufa-based "Prombusinessgroup", which attempted to register the trademark of the Soviet cigarettes "Belomorkanal" for itself, continues its assault on public trademarks. This time, the company wants to acquire rights to the brand "Analgin." (...)
In our country, "Analgin" has been synonymous with the word "analgesic" since Soviet times. More than 50 pharmaceutical companies produce Analgin on the Russian market.
The medicine is one of the most popular in the market. According to research company "Pharmexpert", 65.4 million packages of medicine branded "Analgin" were sold between January and October 2011, amounting to $31.2 million.
— "A company from Ufa is trying to register the "Analgin" brand for itself" (in Russian) - (English translation) - December 22, 2011