Talk:Malignant rhabdoid tumour

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note

Someone please clarify in the article: are malignant rhabdoid tumor (MRT) and rhabdoid tumor the same thing? Or is MRT a subset? Ie, are some rhabdoid tumors benign? --Una Smith 04:02, 20 October 2007 (UTC)[reply]

Below is some text from the ATRT article, that more properly belongs in this article. Someone please work it into the article. --Una Smith 04:04, 20 October 2007 (UTC)[reply]

Malignant rhabdoid tumor (MRT) was initially described in 1978 as a rhabdomyosarcomatoid variant of Wilms' tumor because of its occurrence in the kidney and because of the resemblance of its cells to rhabdomyoblasts.^[1] The absence of muscular differentiation led Haas and colleagues^{[citation needed]} to coin the term "rhabdoid tumor of the kidney" in 1981. Although renal MRT was historically included in treatment protocols of the National Wilms Tumor Study (NWTS) Group, this tumor is now recognized as separate from a Wilms tumor. In contrast to a Wilms tumor, an MRT of the kidney is characterized by early onset of local and distant metastases and by resistance to chemotherapy. Whereas the overall survival rate for Wilms tumors exceeds 85%, the survival rate for renal MRTs is only 20-25%. MRT is one of the most aggressive and lethal malignancies in pediatric oncology. Since rhabdoid tumor of the kidney was originally described, malignant rhabdoid tumors have been reported in practically every location in the body, including the brain, liver, soft tissues, lung, skin, and heart.

Now this section is completely devoid of citations and contains apparent nonsensical use of jargon, "Taxon". C4dn (talk) 16:44, 11 March 2021 (UTC)[reply]

References

^ Beckwith JB, Palmer NF (1978). "Histopathology and prognosis of Wilms tumors: results from the First National Wilms' Tumor Study". Cancer. 41 (5): 1937–48. PMID 206343.

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[1] Beckwith JB, Palmer NF (1978). "Histopathology and prognosis of Wilms tumors: results from the First National Wilms' Tumor Study". Cancer. 41 (5): 1937–48. PMID 206343.

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