Talk:Lugdunin

Pharmacology Low‑importance

	This article is within the scope of WikiProject Pharmacology, a collaborative effort to improve the coverage of Pharmacology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.PharmacologyWikipedia:WikiProject PharmacologyTemplate:WikiProject Pharmacologypharmacology articles
Low	This article has been rated as Low-importance on the project's importance scale.

Chemicals Start‑class Low‑importance

	This article is within the scope of WikiProject Chemicals, a daughter project of WikiProject Chemistry, which aims to improve Wikipedia's coverage of chemicals. To participate, help improve this article or visit the project page for details on the project.ChemicalsWikipedia:WikiProject ChemicalsTemplate:WikiProject Chemicalschemicals articles
Start	This article has been given a rating which conflicts with the project-independent quality rating in the banner shell. Please resolve this conflict if possible.
Low	This article has been rated as Low-importance on the project's importance scale.

Incorrect structure

The chemical structure in Chemspider database with ID 57427034, despite being named "Lugdunin" there, and "verified by users", does not correspond with the structure published in referenced Nature article (chemspider's structure has additional cysteine in the macrocycle).

I have redrawn the structure: File:Lugdunin.svg. I am currently unable to generate InChI or SMILES strings with proper stereochemistry, however the SVG file contains chemical structure information and can be directly opened in BKChem and exported to different formats.
--Mykhal (talk) 23:04, 28 July 2016 (UTC)[reply]

This is now resolved. I've fixed the structure on [ChemSpider], and The chemistds has updated this article's ChemBox with the correct SMILES, InChI, etc. WildCation (talk) 12:29, 1 August 2016 (UTC)[reply]

Corrected table of NRPS genes

The first version of the table of NRPS genes was incorrect because LugA, B, C, and D are not strictly consecutive. I corrected this.

The GenBank records are archival, from a complete genome sequencing project, and may never be updated to reflect lugdunin biochemistry. So I added links to RefSeq entries, which can be updated at will by RefSeq staff.

Extended data Fig 1 describes additional genes upstream of LugA, namely LugJIEFGH, several of which are involved in transport. But those are not well characterized enough to add to the table. That might be too much detail about incomplete characterized genes, so I did not add. — Preceding unsigned comment added by Daniel haft (talk • contribs) 11:26, 4 August 2016 (UTC)[reply]