Talk:Lornoxicam

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Three of the most commonly employed substrate probes for determining CYP2C9 activity in crude human tissue fractions are (S)-warfarin (7-hydroxylation), tolbutamide (methylhydroxylation), and diclofenac (4-hydroxylation). And the best in vivo probes for CYP2C9 activity are tolbutamide and flurbiprofen. Turnover of (S)-warfarin and tolbutamide by CYP2C9 is extremely slow. Conversely, diclofenac has the advantage that CYP2C9 catalyzes its metabolism with a high turnover number, but is not a useful in vivo probe for CYP2C9.

--ἀνυπόδητος (talk) 12:40, 17 December 2010 (UTC)[reply]

This text was part of a WP:NOT PAPERS sounding section ("We suggest lornoxicam as a good Probe for CYP2C9, both In Vitro and In Vivo..."). --ἀνυπόδητος (talk) 13:41, 17 December 2010 (UTC)[reply]