Talk:Lorcainide
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Citation style
[edit]The reference list in this article may prove a bit difficult to maintain in the long run, since it all has to be updated manually. I propose moving it to WP:List-defined references using standard footnotes. That will keep the bulky part of the citations out of the text, but permit automatic numbering. Does anyone object? WhatamIdoing (talk) 14:36, 15 June 2013 (UTC)
- I'd support that proposal. The use of templates for citations simplifies the use of tools to spot errors and makes maintenance and updating easier and LDRs make the wikitext in a well-referenced article much more readable. --RexxS (talk) 22:02, 15 June 2013 (UTC)
Negative Data, Publication Bias, and 100,000 Deaths Controversy
[edit]Um... conspiracy isn't my thing, but is there any reason the very well published controversy involving publication bias, hidden data, and over 100,000 deaths related to Lorcainide is not mentioned in this article?[1][2][3][4][5][6][7][8]Joel S Bateman (talk) 21:01, 13 August 2015 (UTC)
References
- ^ "Bad pharma: Drug research riddled with half truths, omissions, lies". Salon.com. 27 January 2013. Retrieved 13 August 2015.
- ^ "The effect of lorcainide on arrhythmias and survival in patients with acute myocardial infarction: an example of publication bias". ncbi.nlm.nih.gov. 1 July 1993. Retrieved 13 August 2015.
- ^ "The Stigma of Negative Results". Science for Fitness. 4 February 2013. Retrieved 13 August 2015.
- ^ "The true lorcainide story revealed". The BMJ. 2 January 2015. Retrieved 13 August 2015.
- ^ "PUBLICATION BIAS: WHY THE DRUGS MIGHT NOT WORK". Endless Trax. 7 October 2012. Retrieved 13 August 2015.
- ^ "100,000 Avoidable Deaths". Cavernoma Alliance UK. 29 August 2014. Retrieved 13 August 2015.
- ^ "Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients". Google Books. 1 January 2012. Retrieved 13 August 2015.
- ^ "Big Pharma Plays Hide-the-Ball With Data". Newsweek. 13 November 2014. Retrieved 13 August 2015.
Synthesis discrepancy
[edit]The final step of the synthesis depicts alkylation of the piperidine ring using isopropylamine, whereas the text says it uses isopropyl bromide. This is a discrepancy that should be addressed. — Preceding unsigned comment added by 2601:184:4200:6AAB:FD9E:25A3:8C18:A94F (talk) 16:50, 14 August 2015 (UTC)