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Talk:List of JWH cannabinoids

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Table

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I guess this should be turned into a table, with columns for CB1, CB2, etc. Tisane talk/stalk 01:52, 7 July 2010 (UTC)[reply]

Redundant table / list

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As of now, the information in the bullet point list below the table is mostly redundant with the information in the table or in the respective articles about the compounds. I'd therefore suggest to remove the bullet point list. Best regards, --Hbf878 (talk) 09:23, 18 September 2018 (UTC)[reply]

Table suggestion

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Hi, this is my suggestion for a future table layout in that all the information that was in the list before (IUPAC, remarks) is kept without making the table too crowded.


JWH Cannabinoids and their Ki values
Name Class Ki at CB1 [nM] Ki at CB2 [nM] Selectivity CLogP Structure IUPAC name remarks
JWH-004 Naphthoylindole 48 ± 13 4 ± 1.5 CB2 (12x) 6.43
(1-hexyl-2-methyl-1H-indol-3-yl)(naphthalen-1-yl)methanone
JWH-007[1] Naphthoylindole 9.5 ± 4.5 2.9 ± 2.6 CB2 (3.3x) 6.01
(2-methyl-1-pentyl-1H-indol-3-yl)(naphthalen-1-yl)methanone
an analgesic chemical from the naphthoylindole family, which acts as a cannabinoid agonist at both the CB1 receptor and CB2 receptors, with some selectivity for CB2 with a Ki of 2.9nM ± 2.6 and 9.5nM ± 4.5 at CB1
JWH-009 Naphthoylindole >10000 141 ± 14 CB2 (>70x) 6.85
(1-heptyl-2-methyl-1H-indol-3-yl)(naphthalen-1-yl)methanone
JWH-011 Naphthoylindole 6.75
(1-(heptan-2-yl)-2-methyl-1H-indol-3-yl)(naphthalen-1-yl)methanone

References

  1. ^ "Naphthoylindoles" reference