Talk:Kallmann syndrome

Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Kallmann syndrome.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

This is the talk page for discussing improvements to the Kallmann syndrome article.
This is not a forum for general discussion of the article's subject.

Put new text under old text. Click here to start a new topic.
New to Wikipedia? Welcome! Learn to edit; get help.

Article policies

Find medical sources: Source guidelines · PubMed · Cochrane · DOAJ · Gale · OpenMD · ScienceDirect · Springer · Trip · Wiley · TWL

Archives: 1: 60 days

Kallmann syndrome was nominated as a Natural sciences good article, but it did not meet the good article criteria at the time (August 26, 2012). There are suggestions on the review page for improving the article. If you can improve it, please do; it may then be renominated.

Medicine: Genetics Low‑importance

	Medicine portal This article is within the scope of WikiProject Medicine, which recommends that medicine-related articles follow the Manual of Style for medicine-related articles and that biomedical information in any article use high-quality medical sources. Please visit the project page for details or ask questions at Wikipedia talk:WikiProject Medicine.MedicineWikipedia:WikiProject MedicineTemplate:WikiProject Medicinemedicine articles
Low	This article has been rated as Low-importance on the project's importance scale.
	This article is supported by the Medical genetics task force.

New gene table with symptoms

^[1]

^[2]

Prevalence (%)	OMIM	Name	Gene	Locus	Clinical features	Syndromes Associated	Inheritance pattern
5^[1], 5-10^[2]	308700	KAL1 (ANOS1)	KAL1	Xp22.3	Anosmia. Digital synkinesia. Unilateral renal agenesis. High arched palate.		x-linked
10^[1]^[2]	147950	KAL2	FGFR1	8p11.23	Cleft lip and / or cleft palate. Septo-optic dysplasia. Skeletal anomomalies. Bimanual synkinesia. Hand / foot malformation. Combined pituitary hormone deficiency. Missing teeth.	Hartsfield syndrome	Autosomal dominant
6-16^[1], 5-10^[2]	146110	GNRHR	GNRHR	4q13.2			Autosomal recessive
6^[1], 5-10^[2]	612370	CHD7	CHD7	8q12.2	Congenital hearing loss. Semicircular canal hypoplasia. Missing teeth. Coloboma. Short stature.	CHARGE syndrome	Autosomal dominant
3-6^[1], <2^[2]	610628	KAL4	PROK2	3p13	Anosmia		Autosomal recessive
3-6^[1], 5^[2]	244200	KAL3	PROKR2	20p12.3	Anosmia. Combined pituitary hormone deficiency.	Morning Glory syndrome	Autosomal recessive
3^[1], 2-5^[2]	615267	IL17RD	IL17RD	3p14.3	Anosmia.Congenital hearing loss.		Autosomal recessive
2^[1], 2-5^[2]	611584	SOX10	SOX10	22q13.1	Anosmia.Congenital hearing loss. Iris hypopigmentation.	Waardenburg syndrome	Autosomal dominant
2^[1], <2^[2]	614842	KISS1	KiSS-1	1q32.1			Autosomal recessive
2^[1], <2^[2]	614837	KISS1R (GPR54)	GPR54	19p13.3			Autosomal recessive
<2^[2]	612702	FGF8	FGF8	10q24.32	Anosmia.Cleft lip and / or cleft palate. Skeletal anomomolies. Bimanual synkinesia. Combined pituitary hormone deficiency. Hearing loss. Hand / foot malformation.		Autosomal dominant
<2^[1], 1 report^[2]	615270	FGF17	FGF17	8p21.3	Anosmia	Dandy-Walker syndrome	Autosomal dominant
<2^[1]	164260	LEP	LEP	7q32.1	Early onset of morbid obesity.		Autosomal recessive
<2^[1]	601007	LEPR	LEPR	1p31.3	Early onset of morbid obesity.		Autosomal recessive
<2^[1]	162150	PCSK1	PCSK1	5q15	Early onset of morbid obesity.		Autosomal recessive
Rare^[1], 1 report^[2]	616030	FEZF1	FEZF1	7q31.32	Anosmia		Autosomal recessive
Rare^[1], 1 report^[2]	616031	CCDC141	CCDC141	2q31.2	Anosmia		Unknown
Rare^[1], <2^[2]	614897	SEMA3A	SEMA3A	7q21.11	Anosmia. Hyposmia		Autosomal dominant
1 report^[2]	608166	SEMA3E	SEMA3E	7q21.11		Anosmia. CHARGE syndrome	Autosomal dominant
Rare^[1]	607961	SEMA7A	SEMA7A	15q24.1			Autosomal dominant
Rare^[1], <2^[2]	614880	HS6ST1	HS6ST1	2q14.3	Anosmia. Cleft lip and / or cleft palate. Skeletal anomalies.		Autosomal dominant
Rare^[1], 1 report^[2]	614858	WDR11	WDR11	10q26.12	Combined pituitary hormone deficiency.		Autosomal dominant
Rare^[1]	614838	NELF (NSMF)	NELF	9q34.3	Anosmia		Autosomal dominant
Rare^[1]	617351	IGSF10	IGSF10	3q24			Autosomal dominant
Rare^[1], <2^[2]	614841	GNRH1	GNRH1	8p21.2			Autosomal recessive
Rare^[1], <2^[2]	614839	TAC3	TAC3	12q3			Autosomal recessive
Rare^[1], 5^[2]	614840	TACR3	TACR3	4q24			Autosomal recessive
Rare^[1]	611744	OTUD4	OTUD4	4q31.21	Cerebellar ataxia.	Gordon Holmes syndrome	Autosomal recessive
Rare^[1]	609948	RNF216	RNF216	7p22.1	Cerebellar ataxia.	Gordon Holmes syndrome	Autosomal recessive
Rare^[1]	603197	PNPLA6	PNPLA6	19p13.2	Cerebellar ataxia.	Gordon Holmes syndrome	Autosomal recessive
1 report^[2]	109135	AXL	AXL	19q13.2	Anosmia		Unknown
Rare^[1]	612186	DMXL2	DMXL2	15q21.2	Polyendocrine deficiencies and polyneuropathy.		Autosomal recessive
Rare^[1]	300473	NR0B1 (DAX1)	NR0B1	Xp21.2	Adrenal hypoplasia.		x-linked
1 report^[2]	602748	DUSP6	DUSP6	12q21.33	Anosmia		Autosomal dominant
1 report^[2]	614366	POLR3B	POLR3B	12q23.3			Autosomal recessive
1 report^[2]	615266	SPRY4	SPRY4	5q31.3			Autosomal dominant
1 report^[2]	615271	FLRT3	FLRT3	20p12.1	Anosmia		Autosomal dominant
1 report^[2]	617264	SRA1	SRA1	19q13.33			Unknown
Rare^[1]	601802	HESX1	HESX1	3p14.3	Septo-optic dysplasia. Combined pituitary hormone deficiency.		Autosomal recessive and dominant

References

^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l ^m ⁿ ^o ^p ^q ^r ^s ^t ^u ^v ^w ^x ^y ^z ^aa ^ab ^ac ^ad ^ae ^af Lima Amato LG, Latronico AC, Gontijo Silveira LF (2017). "Molecular and Genetic Aspects of Congenital Isolated Hypogonadotropic Hypogonadism". Endocrinol Metab Clin North Am. 46 (2): 283–303. doi:10.1016/j.ecl.2017.01.010. PMID 28476224.{{cite journal}}: CS1 maint: multiple names: authors list (link)
^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l ^m ⁿ ^o ^p ^q ^r ^s ^t ^u ^v ^w ^x ^y ^z ^aa ^ab Balasubramanian R, Crowley WF Jr (2017). "Isolated Gonadotropin-Releasing Hormone (GnRH) Deficiency". SourceGeneReviews® [Internet]. PMID 20301509.

[pmid:28476224-1] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l ^m ⁿ ^o ^p ^q ^r ^s ^t ^u ^v ^w ^x ^y ^z ^aa ^ab ^ac ^ad ^ae ^af Lima Amato LG, Latronico AC, Gontijo Silveira LF (2017). "Molecular and Genetic Aspects of Congenital Isolated Hypogonadotropic Hypogonadism". Endocrinol Metab Clin North Am. 46 (2): 283–303. doi:10.1016/j.ecl.2017.01.010. PMID 28476224.{{cite journal}}: CS1 maint: multiple names: authors list (link)

[pmid:20301509-2] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l ^m ⁿ ^o ^p ^q ^r ^s ^t ^u ^v ^w ^x ^y ^z ^aa ^ab Balasubramanian R, Crowley WF Jr (2017). "Isolated Gonadotropin-Releasing Hormone (GnRH) Deficiency". SourceGeneReviews® [Internet]. PMID 20301509.

[1]

[2]