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This article was the subject of a Wiki Education Foundation-supported course assignment, between 10 January 2022 and 4 February 2022. Further details are available on the course page. Student editor(s): Arwinter23 (article contribs). Peer reviewers: Sam6836.

Wiki Education Foundation-supported course assignment

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This article is currently the subject of a Wiki Education Foundation-supported course assignment, between 10 January 2022 and 4 February 2022. Further details are available on the course page. Student editor(s): Arwinter23.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 00:27, 17 January 2022 (UTC)[reply]

start

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See edit 4th July. Are PPIs questionably effective for heartburn or is the evidence better than that?Mark 07:23, 5 July 2007 (UTC)

Generally recognized as safe and effective per the sourced PPI page. Edited accordingly (2.5 years later!). --Elvey (talk) 19:59, 5 November 2009 (UTC)[reply]

Will it cause upset stomach? Will it cause some serious illness? Mrp8196 (talk) 15:14, 13 January 2014 (UTC)[reply]

symptom

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Dyspepsia is a symptom rather than a disease. Cochrane defines it as heartburn and or epigastric pain. http://www.ncbi.nlm.nih.gov/pubmed/16235292 Doc James (talk · contribs · email) 02:59, 21 April 2010 (UTC)[reply]

That seems like an overly limited definition. The medical dictionary has broader definition, which is "painful, difficult, or disturbed digestion, which may be accompanied by symptoms such as nausea and vomiting, heartburn, bloating, and stomach discomfort". Apparently there was even a 1986 conference meeting which studied the definition. I'm interested in seeing what this 2010 review has to say, but unfortunately don't have access.. think you could possibly send it to me? No pressure. II | (t - c) 21:55, 6 November 2010 (UTC)[reply]
Been reading a bit more about this and studies definitely include symptoms like nausea, early satiety or postprandial fullness, etc. in their definitions of dyspepsia. Treating Helicobacter pylori infection in primary care patients with uninvestigated dyspepsia: the Canadian adult dyspepsia empiric treatment—Helicobacter pylori positive (CADET-Hp) randomised controlled trial is an interesting article, and it mentions that "eradication of H pylori also relieved epigastric pain or discomfort and belching symptoms but not heartburn, regurgitation, bloating, nausea, early satiety, or postprandial fullness (data not shown)". II | (t - c) 01:08, 7 November 2010 (UTC)[reply]
There's a review of Japanese herbal treatments which show that several are pretty promising. Not many clinical trials though so I held off on putting it in the article, but very interesting. II | (t - c) 19:57, 3 January 2011 (UTC)[reply]

treatment

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Ingestion of PPI over a long period (some years) may cause in nerve diseases. The reason is, that vitamin B12 may not be uptaked/utilized enough because of lack of an intrinsic factor produced together with the stomac-acid. I myself got polyneuropathy (PNP) in feet (ingestion of Omeprazol over a period of > 7 years, 20 mg/d). Reducing the Omeprazol to 20 mg every 2...3...4...5 days (withdrawing) and infusion of B12 + Folic acid + B6 + B2 caused in very slow improvement (needs some years) of the feet-symptoms. My physicians (including neurologist) are convinced that the PPI´s are responsible for the PPN. Researching in internet one will finde some literature about these possible side effects of PPI´s.Anna Bolaine (talk) 06:57, 25 September 2013 (UTC)[reply]

Functional dyspepsia

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NEJM doi: 10.1056/NEJMra1501505 JFW | T@lk 21:56, 7 November 2015 (UTC)[reply]

signs and symptoms

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The signs and symptoms section doesn't have ... signs or symptoms. — Preceding unsigned comment added by 99.240.51.235 (talk) 00:25, 24 January 2017 (UTC)[reply]

Luckily, they were listed at the start of the article. Seems like a perfectly smart and sensible decision. I suggest moving the rest of the article there, too, and filling all the subsections with meaningless drivel which can only be understood by medical experts. — Preceding unsigned comment added by 2003:65:E80D:D969:74D8:CD50:63A:49EB (talk) 20:21, 11 March 2018 (UTC)[reply]

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Hi everyone! UCF WikiProject MS4 student here.

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Hello everyone - I am currently an MS4 medical student taking a WikiProject course. I am posting my workplan below and would love your feedback/assistance:
Introduction: I plan to update a few of the citations. For example, an old citation from 2004 is used to support following up new onset indigestion with endoscopy and there are updated guidelines from 2017 that should be cited. Additionally, statistics that are mentioned are >5yrs old and I plan to find more up-to-date statistics to describe the prevalence of indigestion.
Signs and Symptoms: There are a few studies mentioned without any references – I plan to find recent studies to support these findings and cite them (if I cannot, I will remove these findings from the article). Additionally, I plan to create a concise list for symptoms and associated symptoms of indigestion.
Causes: I hope to improve this section in a number of ways. Upon first review, I notice it states that a majority of indigestion is caused by GERD and gastritis, but I would like to see if I can find concrete and recent statistics to support this claim. As per other sections, there are a few statistics mentioned throughout this section without any references to the source – I aim to update and add citations for these claims. Secondly, I plan to begin the section by categorizing dyspepsia and then create secondary headers for “organic” vs “functional” indigestion. Under “organic” will be peptic ulcers, GERD, cancers, pancreatic and biliary disorders, intolerance to food or drugs, and other infectious or systemic diseases. Under “functional” will be postprandial distress syndrome and epigastric pain syndrome. I aim to make these sections as patient-friendly as possible, with limited medical jargon. Lastly, I would like to add a “risk factors” section either at the beginning of the section or under each individual subsection.
Pathophysiology: This section reads more like a connection between indigestion and psychological disorders instead of pathophysiology. I think the previous author was trying to explain that the pathophysiology is not well understood – however, this section could use a bit of a re-write. I plan to use a 2020 article from The Lancet as my source and provide a brief, but clear explanation of the pathophysiology.
Diagnostic Approach: This section is rather short, so I’d like to clarify the process of diagnosing the cause of indigestion. If I were a patient, I would want to better understand why my doctor ordered X test and/or Y medication. I will peruse some medical textbooks and find more recent meta-analysis literature (the citation in this section is from 2006) so I can better explain how physicians decide the cause of a patient’s indigestion (e.g., what symptoms are they looking for in the H&P, what tests are being ordered and why). I also think this section would benefit from an image, such as a diagnostic algorithm.
Management: I like how this section is laid out, but it could benefit from an update to its sources. Additionally, the “diet” section is sparse and could be elaborated on. I’d like to review the literature and find current guidelines for diet outside of the brief sentence that I believe is referring to celiac disease. Lastly, the alternative medicine section cites literature from the early 2000s so I will aim to find more up-to-date meta-analysis or reviews pertaining to alternative treatments for indigestion.
Epidemiology: I wanted to add an epidemiology section, using the “chest pain” wiki page as a guide. I hope to find relevant and recent statistics to show how commonly patients present with this problem.

I would love any and all feedback - thank you! Arwinter23 (talk) 21:17, 12 January 2022 (UTC)[reply]

Hello Arwinter23,
I’m happy to provide a peer review. The addition of updated information in the introduction provides an improved lead to the article. In the signs and symptoms section, the list of signs that you included was helpful. I was specifically impressed by the cause and diagnosis sections. The way that you restructured the cause section into organic vs functional indigestion made it more understandable. The image that you included does a fantastic job of providing readers with a guide on the diagnosis and treatment of indigestion. The changes that you made to the pathophysiology, treatment, and epidemiology sections were also great and provided pertinent information.
The diagnosis section may benefit from including intext links to other articles for keywords. Also, certain sentences are a bit lengthy (e.g., last sentence of diagnosis paragraph) and may benefit from being shortened or separated into two sentences. Overall, you did an excellent job on this article! The work you did on the article made it more readable, structured, and comprehensive.
Sam6836 (talk) 01:49, 2 February 2022 (UTC)[reply]