Talk:Immunogenicity

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Wiki Education Foundation-supported course assignment

This article was the subject of a Wiki Education Foundation-supported course assignment, between 7 January 2020 and 12 March 2020. Further details are available on the course page. Student editor(s): Immcarle106.

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Information from 2019

Hello,

I was wondering if there was any additional recent, reliable sources to read more about Immunogenicity on. I noticed that there was only 1 source from 2018. Also, I am curious what information is exactly being pulled from The European Immunogenicity Platform website.

ThanksImmcarle106 (talk) 21:49, 29 January 2020 (UTC)[reply]

Additional Information/References to the Article

Hello,

I plan to add additional information to the article using the following sources/references:

Wesselhoeft, R.A., Kowalski, P.S., Parker-Hale, F.C., Huang, Y.X., Bisaria, N., and Anderson, D.G. (2019). RNA Circularization Diminishes Immunogenicity and Can Extend Translation Duration In Vivo. Mol Cell 74, 508-+. --- The immunogenicity stability of circRNA preparations are found to be dependent on purity, with small amounts of contaminating linear RNA leading to robust cellular immune responses. Additionally, unmodified circRNA is less immunogenic than unmodified linear mRNA partially because of evasion of TLR and RIG-I sensing.

Lindsey, B.B., Armitage, E.P., Kampmann, B., and de Silva, T.I. (2019). The efficacy, effectiveness, and immunogenicity of influenza vaccines in Africa: a systematic review (vol 19, pg e110, 2019). Lancet Infect Dis 19, E187-E187. -- Some vaccines, such as rotavirus and oral polio vaccines, show that efficacy and immunogenicity data from High-income countries are not always transferable to low-income and middle-income countries (LMICs)

Lochlainn, L.M.N., de Gier, B., van der Maas, N., Strebel, P.M., Goodman, T., van Binnendijk, R.S., de Melker, H.E., and Hahne, S.J.M. (2019). Immunogenicity, effectiveness, and safety of measles vaccination in infants younger than 9 months: a systematic review and meta-analysis. Lancet Infect Dis 19, 1235-1245. --Immunogenicity of some vaccinations being age-dependent, including infants.

Samson, S.I., Leventhal, P.S., Salamand, C., Meng, Y., Seet, B.T., Landolfi, V., Greenberg, D., and Hollingsworth, R. (2019). Immunogenicity of high-dose trivalent inactivated influenza vaccine: a systematic review and meta-analysis. Expert Rev Vaccines 18, 295-308. --Immunogenicity of some vaccinations being age-dependent, including older ages.

Immcarle106 (talk) 21:22, 2 February 2020 (UTC)[reply]

Merger proposal

88.112.30.115 proposed to merge Antigenicity into Immunogenicity but forgot to create this discussion. CutePeach (talk) 13:48, 3 April 2021 (UTC)[reply]

Weak support - Same topic but, but from multidisciplinary viewpoint, antigenicity implies more emphasis on antigens properties while immunogenicity looks more at immune networks. CutePeach (talk) 14:01, 3 April 2021 (UTC)[reply]
Redirect to wiktionary? The article is pretty definitional. --Tom (LT) (talk) 05:53, 4 April 2021 (UTC)[reply]
Support merge as stated; synonyms, with Antigenicity being a stub; best discussed on one page. Klbrain (talk) 09:48, 1 September 2021 (UTC)[reply]
There's also the similarly stubby immunogen, and inconsistent redirects: Antigenic → antigen, but immunogenic → immunogenicity. I support cleaning this up, but I think I'd actually merge immunogen here, and antigenicity to antigen. Opabinia regalis (talk) 07:57, 20 September 2021 (UTC)[reply]

I note the alternative proposal by Opabinia regalis, and accept that the alternative target would be a good idea. However, given that this alternative target has had no support over more than 11 months, I've gone ahead with the proposal as initially proposed. I agree that some changes to the redirects might be warranted;

Merger complete. Klbrain (talk) 02:40, 31 August 2022 (UTC)[reply]