A fact from Hypertryptophanemia appeared on Wikipedia's Main Page in the Did you know column on 23 November 2008 (check views). The text of the entry was as follows:
The following quoted paragraph is confusing. Is hypertryptophanemia associated with a decrease, or with an increase, of kyneuric acid?
"One of these kynurenines, aptly named kynurenic acid, serves as a neuroprotectant through its function as an antagonist at both nicotinic and glutamate receptors (responsive to the neurotransmitters nicotine and glutamate, respectively).[11][12] This action is in opposition to the agonist quinolinic acid, another kynurenine, noted for its potential as a neurotoxin.[10][13] Quinolinic acid activity has been associated with neurodegenerative disorders such as Huntington's disease, the neuroprective abilities of kynurenic acid forming a counterbalance against this process, and the related excitotoxicity and similar damaging effects on neurons.[13][14]" — Preceding unsigned comment added by 2001:8003:3C98:600:6DC5:D631:BDD7:36C1 (talk) 03:02, 24 October 2017 (UTC)[reply]
