Talk:Humouse

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Request for deletion

This article should be deleted because nobody uses the term "humouse". The term Humanized mouse is used in biomedical research literature. Anyway it's a stub with no useful information. Xenobiologista (talk) 17:13, 14 August 2014 (UTC)[reply]

Request for Update

Rather than delete this entire page I believe it should be updated. It would be more accurate to name this page "SCID-hu mouse" or "humanized immunodeficient mice." Further applications of SCID-hu mouse models should be added, such as their use in studying viral infections like HIV or the process of hematopoiesis as they would happen in humans. More information on the creation of these mice should be added, as well as different types of SCID-hu mouse models.

I have compiled a list of references that could be helpful in updating this page below.

Bibliography:

1. McCune, Joseph M. "Development and applications of the SCID-hu mouse model." Seminars in Immunology 8, no. 4 (August 1996): 187-96. http://www.sciencedirect.com/science/article/pii/S104453239690024X?via%3Dihub.

2. Camacho, Ramon E., Richard Wnek, and Paul Fischer. "Characterization of the NOD/scid-[Tg]DR1 mouse expressing HLA-DRB1∗01 transgene: a model of SCID-hu mouse for vaccine development." Experimental Hematology 35, no. 8 (August 2007): 1219-230. http://www.sciencedirect.com/science/article/pii/S0301472X07002913.

3. Wang, Emilie-Jeanne, Massimo Petoello-Mantovani, and Christina M. Anderson. "Development of a Novel Transgenic Mouse/SCID-hu Mouse System to Characterize the In Vivo Behavior of Reservoirs of Human Immunodeficiency Virus Type 1–Infected Cells." The Journal of Infectious Diseases 186, no. 10 (November 15, 2002). doi:https://doi.org/10.1086/344737.

4. Brehm, Michael A., Leonard D. Shultz, and Dale L. Greiner. "Humanized Mouse Models to Study Human Diseases." HHS Author Manuscripts, April 2010. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892284/.

5. Van Duyne, Rachel, Caitlin Pedati, and Irene Guendel. "The utilization of humanized mouse models for the study of human retroviral infections." Retrovirology, August 12, 2009. doi:10.1186/1742-4690-6-76.

6. Brehm, Michael A., Amy Cuthbert, and Chaxing Yang. "Parameters for establishing humanized mouse models to study human immunity: Analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rγnull mutation." Clinical Immunology 135, no. 1 (April 2010): 84-98. http://www.sciencedirect.com/science/article/pii/S1521661609009164.

7. Okada M. et al. (2006) Development of Vaccines and Passive Immunotherapy Against Sars Coronavirus Using Mouse and Scid-PBL/hu Mouse Models. In: Perlman S., Holmes K.V. (eds) The Nidoviruses. Advances in Experimental Medicine and Biology, vol 581. Springer, Boston, MA. http://link.springer.com/chapter/10.1007%2F978-0-387-33012-9_102

Immcarle43 (talk) 17:39, 29 January 2017 (UTC)[reply]

?

Should this include the PBL-SCID mice? Or is it specifically for transgenic mice, like the huCD4+ tg mice? WhatamIdoing 20:23, 17 October 2007 (UTC)[reply]

maybe it should be included with Mickey Mouse, Mighty Mouse, Speedy Gonzales, and other anthropomorphic mice :) —Preceding unsigned comment added by 167.7.17.3 (talk) 13:32, 6 April 2009 (UTC)[reply]

No, a knockout mouse has nothing to do wih Mighty Mouse, or Hippety Hopper for that matter. For that, see Anthropomorphism#Film and television and Funny animal and Furry fandom. --Damian Yerrick (talk | stalk) 01:06, 13 April 2013 (UTC)[reply]

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