Talk:Homeobox protein NANOG

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informatics wiki information on nanog

our class has been working on this gene and many others. since this ariticle is not as detailed as ours, i wanted to suggest looking at ours https://tyrosine.umdnj.edu/wiki/index.php/NANOG and using our info in here. I think it would help out a great deal. I was going to copy paste the entire article here, but since we are novices i think it would be better to have some more experienced wiki-people to make the decisions.

I would like to add some information about the role of NANOG on Canser stem cells Rehab.Gharawi (talk) 15:21, 12 November 2018 (UTC)[reply]

NANOG role in generation of PGCs

New report that NANOG alone can can induce PGC-like cells in epiblast-like cells, independently of BMP4, which has been previously shown to induce PGC-like cells in epiblast-like cells. The authors found genome-wide changes in NANOG-binding patterns between ES cells and EpiLCs, indicating epigenetic resetting of regulatory elements, and revealing a mechanistic principle for the context-dependent roles of key transcription factors during development. ^[1] B82mo (talk) 07:12, 15 January 2016 (UTC)[reply]

References

^ NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers, Kazuhiro Murakami et al., 2016, Nature

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[1] NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers, Kazuhiro Murakami et al., 2016, Nature

[1]