Talk:Glimepiride

Pharmacology Mid‑importance

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Medicine Mid‑importance

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Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Glimepiride.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

What?

This article is half gibberish and half broken english. Someone who actually understands this needs to fix it. AeoniosHaplo 19:16, 18 May 2007 (UTC)[reply]

Not all criticism is useful. This article is perfectly clear as far as it goes, but contains insufficient data on the drug's development, interactions, side-effects, and contraindications, and there should be some discussion of its use in combination with other drugs. This is particularly important since many physicians employ a combination therapy (e.g., a sulfonylurea and metformin) and since many type II diabetics also have cardiovascular or renal problems. In this context, more information concerning the interaction with thiazides would be especially salient. — Preceding unsigned comment added by JIMPARKS (talk • contribs) 20:09, 17 December 2011 (UTC)[reply]

Half-life

What's the biological half-life? The article says it's 5 hours. My primary care physician said it's closer to 9-10 hours. I think the article could be improved with a citation to appropriate research -- especially if 5 hours is wrong. I understand that the reality could be more complicated than simple exponential decay. Glimepiride might go through several stages in the body, and the ingested form might have a half-life of 5 hours but half of a subsequent form could still be present 10 hours later. Thanks, DavidMCEddy (talk) 22:39, 30 September 2015 (UTC)[reply]