Talk:Furosemide

Hepatic cirrhosis

In hepatic cirrhosis, Furosemide effects are often reaborbed due to the hyperaldosteronism (Renin-angiotensin-aldosterone). Thus, I believe spironolactone is the drug of choice. —Preceding unsigned comment added by Koene (talk • contribs) 04:46, 30 March 2008 (UTC)

Can someone add this in the right spot

In 1993 Neways was forced to recall a weight loss product, as it was found to contain a potentially fatal dose of the prescription diuretic furosemide .

gioto (talk) 11:26, 4 May 2009 (UTC)

Wow, I've heard of various weight loss diets being nothing more than ways of losing retained water before, but that takes the cake... (no pun intended) 193.63.174.11 (talk) 14:06, 4 February 2011 (UTC)

References

Problem with second paragraph under mechanism of action

Due to the large NaCl absorptive capacity of the Loop of Henle and the fact that diuresis is not limited by development of acidosis, as it is with the carbonic anhydrase inhibitors.

A careful reading of this reveals it to be a sentence fragment with no main clause. I suspect the author intended to make a point about the superiority of Na/K-2Cl symporter inhibitors as diuretics compared to carbonic anhydrase inhibitors. That is my best guess. Can some one more knowledgeable in the field clarify this sentence, please? —Preceding unsigned comment added by Eesnyder24060 (talk • contribs) 01:51, 2 June 2009 (UTC)

I would also like to add that the mention of hypocalcaemia not being an issue with Furosemide is not supported by the BNF, which lists both hypocalcaemia and hypomagnesaemia as potential side-effects. Until a citation is provided to contradict the BNF, we should remove any statement that contradicts this. —Preceding unsigned comment added by 92.4.121.143 (talk) 20:01, 5 May 2010 (UTC)

Use in diagnosis of renal conditions?

Worth putting in something about that? It's certainly used to gain certain differential diagnoses in radioisotope scanning (imaging & statistical), and - though my knowledge is a lot shakier in that regard - probably contrast X-ray imaging as well. IE if low or no significant activity is seen at first, does the kidney flush through better/at all with diuretic (higher nephrotic activity, greater fluid pressure) even if it doesn't without it?

Notable enough? 193.63.174.11 (talk) 14:15, 4 February 2011 (UTC)

too technical

This is an example of a common type of Wikipedia medical article that is essentially impenetrable to the lay public. My 4 week old daughter was on this drug. Would someone care add a few sentences explaining in layman's terms where it came from and what it does? E.G: Lasix is a medicine that reduces blood pressure by removing water from your system by making you pee a lot. Jeffrw (talk) 09:10, 27 March 2014 (UTC)

I agree with Jeffrw that this and so many other WP articles are too jargony and technical for casual readers, the vast majority of the people who come to these articles. Making technical words into links to other WP articles to define is fine, but not a solution for incomprehensible language. Linking, by itself, merely creates a frustrating, time-consuming ping-pong way of trying to eek out information the reader is interested in. I would be happy with these kinds of articles if they were at least plain language in the beginning and then, for people who want to read further, to become more technically challenging in the second half. Thank you, Wordreader (talk) 19:32, 3 September 2014 (UTC)

NOTE: The wandering reference below seems to go along with the "Can someone add this in the right spot" thread above. Wordreader (talk) 19:35, 3 September 2014 (UTC)

Cross-reaction?

Since furosemide is a sulfonamide, do people allergic to sulfa drugs (not a small number) also have a cross-allery to furosemide and related diuretics? (Those sneaky sulfa molecules are hiding inside of many non-antibiotic medications.) Thank you, Wordreader (talk) 19:50, 3 September 2014 (UTC)

Interestingly, the general loop diuretic article mentions this, under adverse effects ("Because furosemide, torsemide and bumetanide are technically sulfa drugs, there is a theoretical risk that patients sensitive to sulfonamides may be sensitive to these loop diuretics. This risk is stated on drug packaging inserts. However, the actual risk of crossreactivity is largely unknown and there are some sources that dispute the existence of such cross reactivity.[13][14]")--Bstard12 (talk) 09:11, 4 December 2015 (UTC)

NOTE: The wandering reference below seems to go along with the "Can someone add this in the right spot" thread above. Wordreader (talk) 19:51, 3 September 2014 (UTC)

Too vague opening

The article opens the identification of the drug with a vague "medication used to treat [a list of indications...]", forcing everyone who just wants to know what furosemide is to do a lengthy read. I replaced the vague "medicine" with a clear "loop diuretic" so that drug class would be clear from the first sentence. Doc James quickly reverted this to the original vague form. Since I rather insist on articles being clear, getting to the point quickly and offering lengthier reads to only those who actually want the lengthy reads, I will revert the identification to "loop diuretic" unless someone provides a good reason not to. --Bstard12 (talk) 14:03, 4 December 2015 (UTC)

We try to write the first sentence in easier to understand English. Hopefully those who know what a loop diuretic is can read two paragraphs. Doc James (talk · contribs · email) 17:35, 4 December 2015 (UTC)

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