Talk:Flibanserin
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Adverse effects
[edit]This article seems to be missing some info, since the adverse effects, especially when combined with alcohol, have been discussed as a serious concern about the drug. I don't want to be too involved in this (conflict of interest) but there's more to be said about the adverse effects than the article currently includes. 166.176.187.184 (talk) 21:34, 21 August 2015 (UTC)
Shouldn't there be information about adverse effects among women receiving a placebo? oldrider (talk) 19:31, 17 October 2015 (UTC)
Just changed the last sentence to "Drinking alcohol while on flibanserin may result in severely low blood pressure (low blood pressure that produced symptoms occurred after 2 glasses of wine occurred in 17%)." 1) removed double 'occurred' 2) changed "after only 2 glasses of wine" to "after 2 glasses of wine" - reason: implications of 'only' (ineligible implication of safe amount of wine). — Preceding unsigned comment added by 88.77.126.133 (talk) 14:18, 28 January 2019 (UTC)
Systematic review and meta-analysis
[edit]... finds the evidence of low quality. doi:10.1001/jamainternmed.2015.8565 JFW | T@lk 08:59, 1 March 2016 (UTC)
Identification of 5-HT1A receptor source of NDDI activity
[edit]I noticed above that in the last couple sentences of the first paragraph under "Activity Profile" (subsection of "Mechanism of Action" section), the article states that the norepinephrine-dopamine disinhibitor (NDDI) activity of flibanserin is the result of its activation of the 5HT1A receptor subtype. My own reading over time has seemed to indicate that the NDDI activity result from activity at 5HT2C. I'm wondering if this is just the result of a misreading of literature. It's also possible that the pharmacological understanding of the serotonin receptors has changed over the years to clarify these receptor differences. — Preceding unsigned comment added by 173.18.57.162 (talk) 22:22, 30 October 2016 (UTC)
BBC News article on this in Egypt
[edit]https://www.bbc.co.uk/news/world-middle-east-46877038
The notable parts for me are:
- Locally produced.
- Over the counter.
- Culture - men are in the main part the purchasers and are happy to do so even after being warned of side effects. "Murad Sadiq, who runs a pharmacy in northern Cairo, says he always explains the side effects to customers but that "they still insist on buying it". "About 10 people a day come in to buy the drug. Most of them are men. Women are too shy to ask for it." — Preceding unsigned comment added by 128.40.214.250 (talk) 10:15, 18 January 2019 (UTC)