Talk:Evolocumab

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Pharmacology Mid‑importance

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Could add clinical trials, side effects and cost

Could add info on clinical trials, side effects and cost - especially since it is being promoted as having fewer side-effects than statins. - Rod57 (talk) 14:04, 11 April 2016 (UTC)[reply]

eg the FOURIER trial only showed a 1.5% to 2% absolute risk reduction for various CV endpoints, and the price is still as high.FOURIER Opens ACC With a Bang - Big LDL reduction, prevents MI, but with big price tag - Rod57 (talk) 18:34, 2 December 2017 (UTC)[reply]

New wider approval

Repatha Wins FDA Approval for Stand-Alone CVD Prevention - Rod57 (talk) 18:34, 2 December 2017 (UTC)[reply]

Deaths covered up

This help request has been answered. If you need more help, you can ask another question on your talk page, contact the responding user(s) directly on their user talk page, or consider visiting the Teahouse.

https://bmjopen.bmj.com/content/12/12/e060172 implies that there was fraud and deaths were covered up. I could use some help covering the issue in the article. I see this kind of shit over and over; I fear my anger may come across in my contributions if I edit directly. (No, no COI, just sick of corruption in medicine.) RudolfoMD (talk) 07:32, 24 October 2023 (UTC)[reply]

@RudolfoMD: Individual studies can be used sometimes and with caution in editing health-related articles on Wikipedia, but the recommendations of MEDRS should be kept in mind.

If you want to propose a change here, on the talk page, rather than editing the article directly, it would allow other editors to weigh in and see if a consensus can be found. — jmcgnh^{(talk) (contribs)} 08:12, 24 October 2023 (UTC)[reply]

Good advice/valid points. Consensus - another reason to seek help. https://bmjopen.bmj.com/content/12/12/e060172.responses has several comments on the paper. In the last one, Amgen was asked to release more info - back in January. Perhaps they have. If so, that would be reassuring; if not, that's a red flag.

Is Altrimetric itself a better source for saying that concerns about mortality rate reporting in the FOURIER study attracted some controversy in the media - https://bmj.altmetric.com/details/140671672/news? You urge me to propose a change, so perhaps saying just that/something like that?

Or should the industry news articles be used, or something else said? (Seems clear these are not the general news media MEDRS discourages.) RudolfoMD (talk) 23:29, 24 October 2023 (UTC)[reply]

Just a note, I have closed the {{help me}}, as this has become a consensus-building process and no longer a one-off help request. I have cross-posted at WT:MED to hopefully get more involvement. Primefac (talk) 08:38, 26 October 2023 (UTC)[reply]