Talk:Ethylphenidate

Cocaethylene

See also: cocaethylene. The chemistry behind the formation of this and ethylphenidate is more or less identical. Fuzzform 08:35, 28 October 2007 (UTC)

Levo-Methylphenidate or Dextro-Methylphenidate?

Is ethylphenidate formed with alcohol and levomethylphenidate or is it formed with alcohol and dextromethylphenidate or both? If both does it form more readily with one or another? Is there levo- & dextro- ethylphenidate too? 4.255.55.241 (talk) 05:20, 13 November 2008 (UTC)

"...whereas the biologically active eutomer d-TMP does not react with ethanol to any significant extent..." 4.242.174.196 (talk) 09:44, 16 September 2009 (UTC)

See, [1], [2], [3], [4]. I haven't read these articles in depth yet.--Literaturegeek | T@1k? 02:19, 17 September 2009 (UTC)

TMP?

The initials "TMP" are not defined. Though I assume it means threo-methylphenidate, someone who knows could clarify. 71.203.125.108 (talk) 21:26, 14 December 2009 (UTC)

Eudysmic ratio?

I have read the article [4](J.o. Medicinal Chemistry, 2005, Vol. 48, No. 8, page 2876-2881) and the values which are used in the paper [4] differs from the one in the article. Also in the Article there is no d-TMP mentioned just the racemic mixture of Methylphenidate. Only for Ethylphenidate are there values for both diastereomers and the racemic mixture. In the table is also a comparison with cocaine which is quite interesting. — Preceding unsigned comment added by EfaceX (talk • contribs) 22:24, 14 January 2012 (UTC)

What is a "superior" eudysmic ratio? The article should say specifically whether it is large or small. Qemist (talk) 11:11, 30 November 2012 (UTC)

Dosage?

both compounds generalize at 10mg/kg, meaning 700mg dose of TEP for a 70kg adult male would be the same as one of TMP? doesn't 700mg sound a bit lethal?

No, this is not lethal. Ld50 is 190mg/kg (death in half the cases) — Preceding unsigned comment added by 89.231.249.27 (talk) 20:48, 9 March 2012 (UTC)

10mg/kg is still an extreme dose. I have eaten 50mg (0.7mg/kg) and it was very very strong. I don't recommend anyone even that much. You need to clarify that 10mg/kg is not a normal dose. For example Ritalin comes in 5 mg, 10 mg tablets. 70 times less. Stephan823 (talk) 22:22, 15 March 2012 (UTC)

I have removed this because it is potentially misleading and dangerous:

TEP is less stimulatory than TMP at 5mg/kg, although both compounds generalize at 10mg/kg. This is suggestive of a noradrenergic stimulatory effect present for TMP at lower doses.

If you want to return it to article then add information that it is not the dosage. Stephan823 (talk) 22:42, 15 March 2012 (UTC)

Analogue of Ketamine?

How could ethylphenidate be considered an analogue of ketamine under Australian law? They have vaguely similar structures, but they're significantly different structurally and completely different pharmacologically. — Preceding unsigned comment added by Exercisephys (talk • contribs) 04:34, 9 January 2013 (UTC)

Table units

The table does not have any units listed. This is confusing and poor form. Testem (talk) 21:10, 21 October 2013 (UTC)

Current UK legality

A TCDO does not put the drug in class B under UK law but in a sort of class D - it is illegal to sell or import but not illegal to possess, though if the police do find it in your possession they are allowed to confiscate it and have it destroyed. This is distinct from class A, B and C in UK law which also penalise possession. It is likely that 1 year from the original ban date it will transition to class A, B or C . Page text need updating?81.2.96.191 (talk) 22:48, 24 July 2015 (UTC)

References

Original research/opinion

The half-life mentioned in the drug infobox isn't cited and is based on 'subjective reports' - I've removed this for now.

The article lede also contains a section about urban legends about the drug, but without citing any sources. Henry Stanley (talk) 23:14, 2 June 2017 (UTC)

Inquiries

dose the drug ETHYLPHENIDATE show positive in urine drug test 91.125.181.76 (talk) 09:30, 2 April 2024 (UTC)