Talk:Cefazolin

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Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Cefazolin.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

Wiki Education Foundation-supported course assignment

This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Mog22, LeiC CP133 G22, KuangK CP133 G22. Peer reviewers: Toastntea21.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 17:02, 16 January 2022 (UTC)[reply]

IUPAC Name and Structure

The structure lacks stereochemistry. The name sis

(6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-{[(pyridin-4-ylsulfanyl)acetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

and the structure should be adjusted to include stereo--ChemSpiderMan (talk) 16:23, 25 May 2008 (UTC)[reply]

Added sections and references

Group 22 changes: -Lead: added trade name, moved mechanism of action into its own section. -Medical uses: added bulleted list of indications for infections, reduced surgery prophylaxis to single statement (there were no references for timing). -Bacterial susceptibility: removed MIC range, separated by gram negative and gram positive, and added statements. -Special populations: section added; then added neonates, elderly, and changes to pregnancy subsections. -Mechanism of action: section added. -Adverse events: added caution for patients experiencing bloody stools. -Brands: removed section. MeyerC G22 (talk) 02:40, 5 November 2015 (UTC)[reply]

UCSF Peer Review 11/09/2015 Neutral Point of View: Yes Verifiable Citations – Yes Recommendations: - Medical uses: Include external links - MOA: Expand on mechanism of action, such as how penicillin binding proteins work (or at least link to PBPs) - Susceptibilities: Provide bulleted list for what is not susceptible, consider separating out intrinsically resistant. - Side Effects: Comment on prevalence, so readers know what is common/rare and the red flags to look out for. Maybe put in % information and reorganize by common/chronic/rare-but-severe. Bulleted list may also help with readablity - Special population is good, maybe link “analphylaxis” to its wiki page to make it more layman-friendly

128.218.42.49 (talk) 20:00, 9 November 2015 (UTC)[reply]

Fact Check Interaction with alcohol

- Please verify the cited reference for this statement:

"As the antibiotic is broken down in the body, it releases free NMTD, which can cause hypoprothrombinemia (likely due to inhibition of the enzyme vitamin K epoxide reductase) and a reaction with ethanol similar to that produced by disulfiram (Antabuse), due to inhibition of aldehyde dehydrogenase.[13] "

Cefazolin is excreted from the body unchanged. It is not broken down. Refs: https://www.drugbank.ca/drugs/DB01327, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e8f40f72-3cf0-43dc-a797-fb98dd8af228, — Preceding unsigned comment added by 205.193.94.40 (talk) 20:03, 10 January 2019 (UTC)[reply]

Uses

It can be used for both pneumonia and endocarditis occasionally per the reference.[1]

Doc James (talk · contribs · email) 11:32, 4 November 2019 (UTC)[reply]

Wiki Education assignment: PHMD 2040 Service - Learning Spring 2023

This article was the subject of a Wiki Education Foundation-supported course assignment, between 2 January 2023 and 30 June 2023. Further details are available on the course page. Student editor(s): Jordynlazic, EriyanTurtle (article contribs).

— Assignment last updated by JustinxLane (talk) 19:04, 2 June 2023 (UTC)[reply]