Talk:Carcinoid

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note

I guess that this page should be fusionated with Carcinod Syndrome

Markers

This page is a bit of a stump. Can someone competent expand on it? Maybe a section about tumour markers and diagnostic? Mortality and impact on life quality? --Jan

There's 3 subjects which need merging/coordinating: carcinoid, carcinoid syndrome and neuroendocrine tumor. At the very least there should be easy links between the 3 Danielbirns (talk) 23:35, 5 February 2011 (UTC)[reply]

carcinoid syndrome

Larry Kvols MD of Moffitt Cancer Center and Research Institute in Tampa, in "Carcinoid Tumors and the Carcinoid Syndrome: What's New in the Therapeutic Pipeline", presented at the Carcinoid Cancer Foundation's Carcinoid Symposium 2002, stresses flushing, diarrhea, CHF, and asthma as the four critical characteristics of carcinoid syndrome.

TH 06:35, 27 July 2006 (UTC)[reply]

I suspect that the writer of this section may be mistaking the 5-10% incidence of carcinoid syndrome among carcinoid patients with a 5-10% incidence of secretion. I don't think that's true. Rather, the majority of carcinoids occur in regions drained by the mesenteric vasculature, leading to metabolism of serotonin to 5-HIAA in the liver before it reaches systemic circulation, preventing the evolution of carcinoid syndrome.

My suspicion is that far more than 10% of carcinoids secrete serotonin. — Preceding unsigned comment added by 155.41.112.1 (talk) 14:45, 1 December 2012 (UTC)[reply]

Markers

There's a list of markers, and a discussion of diagnosis, at neuroendocrine tumor.

TH 01:35, 29 July 2006 (UTC)[reply]

please check Neuroendocrine Tumor article

See the neuroendocrine tumors discussion page for statistical citations.

I invite all interested parties to edit or criticize neuroendocrine tumors. Citations are on its discussion page.

TH 02:17, 16 August 2006 (UTC)[reply]

Most common site of incidence of carcinoids is not the appendix!

As per the PAN-SEER data, the most common site for carcinoids is the foregut; bronchial carcinoids constituting the most common ones! Midgut is second in line with ileum constituting the second most prevalent site. And hindgut with rectum alone constitutes 13.6% cases. The appendix constitutes only 4.8% of all cases!

I have made the necessary corrections for this is evident in even the latest textbooks of medicine! —Preceding unsigned comment added by 122.162.87.106 (talk) 23:08, 6 September 2007 (UTC)[reply]

Serotonin Synthesis of Carcinoid

Serotonin is synthesized from the amino acid tryptophan. Tryptophan is also used to synthesize niacin. In carcinoid, a larger percentage of the tryptophan is converted to serotonin. This can lead to a niacin deficiency leading to the development of pellagrous symptoms. —Preceding unsigned comment added by 152.33.56.0 (talk) 02:12, 28 February 2008 (UTC)[reply]

Carcinoid

My corrections would be. Interferon is sometimes helpful, not a regular treatment 2015. The article states 6% incidence of Carcinoid Syndrome. This happens usually when the cancer has spread to the liver or elsewhere, usually. Think the incidence is much higher than 6% All Carcinoids "have malignant potential", I think it is correct to say all carcinoids are malignant. 74.92.16.141 (talk) 04:07, 27 July 2015 (UTC) 74.92.16.141 (talk) 04:10, 27 July 2015 (UTC)[reply]

1 out of 5 males?

Causes reads: "Carcinoid syndrome involves multiple tumors in one out of five males." Please clarify - for the sake of us female patients:) DyslexicDeficit (talk) 10:08, 5 January 2022 (UTC)[reply]