Talk:CA19-9

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Molecular Biology: MCB

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Need some cleanup by knowledgeable experts

The piecemeal nature of the first paragraph is confusing to someone with no a priori knowledge of the subject. "It's a tumor marker, but it may not useful for diagnosis, especially for pancreatic cancer, but it is useful for monitoring progress, but there are other factors that can cause it to be elevated, but sometimes it's not elevated even in advanced cases of cancer. And it was found (for the first time?) in patients with x and y cancer (which is significant why?) in 1981."

In other words, the article needs to stop, take a breath, and figure out what it wants to say. Tlesher (talk) 18:37, 1 July 2008 (UTC)[reply]

Valid point. I have restructured it. It is most certainly relevant that it was first discovered in two types of cancer, if anything for historical purposes. JFW | T@lk 20:29, 1 July 2008 (UTC)[reply]

relevant papers

[http://cancerres.aacrjournals.org/content/45/12_Part_1/6453.full.pdf Detection of Tumor-associated Antigens in the Sera of Lung Cancer Patients by Three Monoclonal Antibodies

Sweetening the Pot:Adding Glycosylation to the Biomarker Discovery Equation

Carbohydrate Antigen Sialyl Lewis a – Its Pathophysiological Significance and Induction Mechanism in Cancer Progression (2009) — Preceding unsigned comment added by Stageivsupporter (talk • contribs) 21:05, 4 April 2011 (UTC)[reply]

I changed "protein" into "antigen" in "Lewis antigen (a blood type antigen on red blood cells" since the Le epitope is of carbohydrate nature and not of protein nature. The carbohydrate is expressed on both lipids and proteins.  — Preceding unsigned comment added by 212.85.66.43 (talk) 06:42, 21 April 2014 (UTC)[reply]