Talk:Butylated hydroxytoluene

BHT as a cure

BHT has been said, and proven to work on herpes and help with other diseases. I also would like to know why there is no information in the article for BHT as a "cure" for many diseases.

"BHT is a suspected mutagen and carcinogen. There have been cases in which some individuals have had difficulty metabolizing BHT, resulting in health and behavior changes."

-- So, we have some assertions here of suspected and observed BHT-related health problems. Anybody care to provide some cites for these? (28 Sept 2005)

-- Also it would be helpful if someone with expertise were to comment on its use in preventing Herpes outbreaks (Simplexes I and II). I have used it for 10 years now for cold sores and it has proven very effective with no short term side effects.

There are many errors in this. BHT was not banned from the UK, and some studies have not proven any increase in cancer risks and actually the opposite.

Yes, I remember reading about one study where rats fed food with BHT lived longer than those without it, presumably due to the compound's ability to neutralize free-radicals.--71.227.190.111 19:32, 25 July 2006 (UTC)

Let's see some citations for all the studies that have shown it's safe. I'm sure there's TONS, right? —Preceding unsigned comment added by 216.14.78.105 (talk • contribs)

That is an unfair comparison, safe chemicals don't appear in studies, because there is no need to (there are more articles about the risks of drowning in water, than about water being safe to drink). But I have added an MSDS which does state that it is an expected carcinogen. --Dirk Beetstra ^{T C} 13:32, 31 August 2006 (UTC)

Yep plenty of info out there on BHT and safety - some positive, and some mixed. I will copy some citations and quotes below: Zarkme (talk) 09:02, 13 September 2013 (UTC)

GM Williams, MJ Iatropoulos, J Whysner (1999) Safety assessment of butylated hydroxyanisole and butylated
hydroxytoluene as antioxidant food additives. Food and Chemical Toxicology, 37 (9-10)
"This review details experimental studies of genotoxicity and carcinogenicity which bear on cancer hazard 
assessment of exposure to humans. We conclude that BHA and BHT pose no cancer hazard and, to the contrary,
may be anticarcinogenic at current levels of food additive use."

Lanigan RS, Yamarik TA. Final report on the safety assessment of BHT(1). Int J Toxicol. 2002;21 Suppl 2:19-94.
"Recognizing the low concentration at which this ingredient is currently used in cosmetic formulations,
it was concluded that BHT is safe as used in cosmetic formulations."
"BHT has been shown to have tumor promotion effects, to be anticarcinogenic, and to have no effect on 
other carcinogenic agents, depending on the target organ, exposure parameters, the carcinogen, and the animal tested"

RS Lanigan, TA Yamarik (1973) Final report on the safety assessment of BHT (1). International journal of toxicology, 23 (3) 295-297
"The mean life-span of male LAF-1 mice when fed BHT (0.5 per cent w of diet)
may be increased by as much as 45 per cent (Harman 1969)
This has been attributed to the antioxidant properties of the chemical and is consistent 
with the free-radical theory of ageing in mammals"

Neal K. Clapp, Lou C. Satterfield, Norman D. Bowles (1979)  Effects of the Antioxidant Butylated
Hydroxytoluene (BHT) on Mortality in BALB/c Mice, Journal of Gerontology, 34 (4), 497-501
"Cumulative mortality curves for mice receiving lifetime BHT treatment and for untreated controls
are shown in Figs. 1 and 2 . Mice receiving BHT generally died at a slower rate than those 
not given BHT , with the primary shift of the curves related to a reduced number of early deaths in 
groups that received BHT"

Hope you guys found the above articles on BHT as interesting as I did! :) Zarkme (talk) 09:02, 13 September 2013 (UTC)

If you have ever read any health magazine then you know there are tons of studies about the health benefits of drinking water, so your argument is not well stated. BHT is an amazing and cheep preservative, if there were conclusive evidence it was safe, then the companies using it would be releasing them to the general public. Instead, they would rather challenge the results of studies which suggest otherwise instead of providing safety data that doesn't exist. Here are two well sited articles that talk about the potential use of BHT as an antiviral agent, and its well established health risks; . It seems clear to me that the FDA has approved it based on studies looking at the risk of BHT consumption in singular food sources, which may be fine for most livers to handle. The real danger of BHT is when people are consuming it regularly from several food sources, and their livers become overstressed. Now of course this claim is not as well supported because these are the studies that are not being provided to the public. Dkriegls 19:05, 6 May 2007 (UTC)

References

Australia

Is this chemical banned in Australia? I am unsure because this document gives directions on how much can be added to certain foods: http://www.foodstandards.gov.au/_srcfiles/FSC_Amend_1_3_1_Part_1_v80.pdf (Mattrix18 00:19, 29 January 2007 (UTC))

BHT use as Peroxideinhibitorin Ether& THF

Can any bodyexplain how BHT use as Peroxideinhibitorin Ether& THF, & the effect ofquantity of BHT?221.135.190.225 12:30, 3 May 2007 (UTC)

Refs

• Branen A. L. (1975). "Toxicology and biochemistry of butylated hydroxyanisole and butylated hydroxytoluene". J Am Oil Chem Soc. 52 (2): 59–63.
• Lanigan R. S., Yamarik T. A. (2002). "Final report on the safety assessment of BHT". International Journal of Toxicology. 21 Supl 2 (5): 19–94. doi:10.1080/10915810290096513.
• Bomhard E. M., Bremmer J. N., Herbold B. A. (1992). "Review of the mutagenicity/genotoxicity of butylated hydroxytoluene". Mutat. Res. 277 (3): 187–200.{{cite journal}}: CS1 maint: multiple names: authors list (link)
• Babich H. (1982). "Butylated hydroxytoluene (BHT): A review". Environmental Research. 29 (1): 1–29. doi:10.1016/0013-9351(82)90002-0.
• Witschi H., Malkinson A. M., Thompson J. A. (1989). "Metabolism and pulmonary toxicity of butylated hydroxytoluene (BHT)". Pharmacol Ther. 42 (1): 89–113. doi:10.1016/0163-7258(89)90023-5.{{cite journal}}: CS1 maint: multiple names: authors list (link)
• F. Shahidi (1989). "Antioxidants in food and food antioxidants". Nahrung/Food. 44 (3): 158–163.

--Stone 15:54, 2 July 2007 (UTC)

colligative props.?

How about freezing point depression constant and stuff like that? colligative properties? —Preceding unsigned comment added by 75.4.225.131 (talk) 01:51, 1 February 2008 (UTC)

I need the colligative properties too. I'm trying to calculate it for a lab report due tomorrow, and I honestly don't know how to do it. —Preceding unsigned comment added by 74.173.243.206 (talk) 07:56, 18 November 2008 (UTC)

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Controversy not about BHT?!?!?!

This page has a section titled "Controversy". The text in this section is almost exactly the same as the section "Controversy" in Butylated_hydroxyanisole, including referring to BHT as E320 (Even though BHT is E321, as stated at the top of the page). Can someone explain this to me? Talk2chun (talk) 12:47, 29 September 2008 (UTC)

I've restored an earlier version of the section. It obviously needs some work, but I think it is better. -- Ed (Edgar181) 13:19, 29 September 2008 (UTC)

Interesting, but you're definitely right, it does need a lot of work. Talk2chun (talk) 23:29, 29 September 2008 (UTC)

"The compound has been banned for use in food in Japan (1958), Romania, and Australia, and in the US it has been banned from use in infant foods." I removed this from the article. The sentence previously included Sweden, but after looking it up [1][2] I found it is very much allowed in Sweden, so I'd suspect the rest of the sentence is badly sourced too. Siawase (talk) 20:41, 23 November 2008 (UTC)

preservative? packaging?

On a cereal box ingredients I have, it says "to preserve the natural wheat flavor, BHT is added to the packaging material." Such a use doesn't seem to be mentioned in the article. Centerone (talk) 20:09, 20 September 2010 (UTC)

Clean up introductory paragraph

The introductory paragraph has an odd sentence, " There is research that links to child hyperactivity as well as to cancer, and conversely, BHT is advocated as a diet supplement and antiviral useful against herpes family viruses." Links what? Links BHT? This is a serious claim that needs to be substantiated. Also it seems to me like the first part of this sentence doesn't belong with the second. Tylerscot (talk) 17:38, 4 April 2013 (UTC)

I agree that the wording of that sentence is unclear and at least partially unsubstantiated so I have removed it. If you think there is a better way of wording this or of summarizing the contents of the "Research" section, please feel to add something of your own back in its place. ChemNerd (talk) 17:49, 4 April 2013 (UTC)

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Natural Occurrence

The claims that BHT is produced in nature are dubious. All the more strange that it is the first sub-paragraph of the article. None of the cited papers in favor of the claim are very thorough or provide any proof that the BHT which was detected was truly of biological origin. Rather, the reports are from not overly well-known institutions and with no follow-up work by the same authors. Since BHT is virtually everywhere, contamination from lab equipment must be considered very likely. A true biosynthetic origin can only be proven through feeding experiments with labeled precursors and by elucidating the biosynthetic pathway. One study was funded by the Tunisian Ministry of Scientific Research. Tunisia is a country that produces lots of olives, and BHT is used to stabilize olive oil (as the article and even the abstract states). So the claim of the article that mold growing on olives is producing BHT would come rather convenient, since any finding of BHT in olive oil could be blamed on molds by the producers...138.246.3.186 (talk) 20:56, 19 November 2020 (UTC)

Companies removing BHT from their products

The paragraph that states some companies have announced that they have or will be voluntarily removing BHT from their products gives absolutely no context. Which companies? Is there a list of products affected by these changes? WHY are they doing it? When were the changes announced? Has it been independently verified? Citing the source of the information is useless when the information itself is useless. It's almost rhetorical. MandieJ1975 (talk) 04:43, 16 June 2021 (UTC)

Updating on carcinogenicity of BHT

I don't think that this section needs an update. Although it states data from the 1970s, it has presented the mainstream opinion regarding this subject as of 2020. And from the literature I viewed (https://kdocs.cn/l/ccGvLYDKWBjw?f=201), it seems that recent discussions are based on the data from the 1970s. Thus, I suggest that this section remains that way, for the old data provide support and historical background for the recent conclusions. However, the sources may still need to be replaced with nonprimary ones. Pygos (talk) 15:11, 14 May 2024 (UTC)