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Talk:Bisphenol A diglycidyl ether

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Health concerns

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Why are the health concerns from this chemical's use as a food can lining so sketchy? Shouldn't its safety have been tested prior to its approval for this use? Do chemicals from the can lining ever migrate into the contents of food cans? 173.88.246.138 (talk) 17:02, 5 March 2021 (UTC)[reply]

BPADGE

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This product is not a solid at the molecular weight stated. It is liquid. I will leave for a few days then I am going to heavily edit if that is OK with everyone? GRALISTAIR (talk) 15:11, 11 January 2023 (UTC)[reply]

Reference[1]

CAS would agree with that (ref). Low level hydrolysis would contaminate it with Bis-HPPP, mpt 89-90°C, which might explain the difference (assuming it's not an error) --Project Osprey (talk) 16:05, 11 January 2023 (UTC)[reply]

What I am trying to do is avoid original research. I could cite my own Master of Science Thesis but that is not appropriate I feel. My company buys railcars of Bisphenol A DiGlycidyl Ether and can assure everyone it is a liquid. We bought a road tanker a day at my previous company. It can be (and is) advanced up with further bisphenol A and an advancement catalyst to higher molecular weight epoxies which are indeed solid. There are multiple suppliers, and I could upload all their technical data sheets but probably over the top and too commercial. There are plenty of peer reviewed journal papers on the subject. I will try and cite those that I have NOT peer reviewed and someone else has. GRALISTAIR (talk) 19:27, 11 January 2023 (UTC)[reply]

Now done. I was not patient! GRALISTAIR (talk) 20:07, 11 January 2023 (UTC)[reply]

I wouldn't worry too much. If your were posting links to your employer that would be COI, citing papers that you're been a reviewer (but not an author) for is fine. It's rare for a page like this to be edited by an expert user with real world knowledge. I would encourage you to be bold. --Project Osprey (talk) 00:26, 12 January 2023 (UTC)[reply]

References

  1. ^ PubChem. "Bisphenol A diglycidyl ether". pubchem.ncbi.nlm.nih.gov. Retrieved 2023-01-11.

Biological activity

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In the section 'N-Terminal domain antagonists' under Antiandrogen#Androgen_receptor_antagonists, I read that:

Examples of AR NTD antagonists include bisphenol A diglycidyl ether (BADGE) [...] [1][2]

That information was introduced by revision [1] in December 2016, and it seems surprising to see no mention of the same information on this page. Is there someone with a modicum of relevant expertise that could check whether it should be included? Hv (talk) 18:29, 19 February 2024 (UTC) Hv (talk) 18:29, 19 February 2024 (UTC)[reply]

References

  1. ^ Imamura Y, Sadar MD (August 2016). "Androgen receptor targeted therapies in castration-resistant prostate cancer: Bench to clinic". International Journal of Urology. 23 (8): 654–665. doi:10.1111/iju.13137. PMC 6680212. PMID 27302572.
  2. ^ Martinez-Ariza G, Hulme C (2015). "Recent advances in allosteric androgen receptor inhibitors for the potential treatment of castration-resistant prostate cancer". Pharmaceutical Patent Analyst. 4 (5): 387–402. doi:10.4155/ppa.15.20. PMID 26389532.
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