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2-Arachidonyl glyceryl ether was a Natural sciences good articles nominee, but did not meet the good article criteria at the time. There may be suggestions below for improving the article. Once these issues have been addressed, the article can be renominated. Editors may also seek a reassessment of the decision if they believe there was a mistake.
The article's lead is not sufficient and does not summarize the article's content. Information should be included about its binding to the CB1 receptor and its biological relevance. (Present the reader with information that will make the reader want to read more)
There were several errors in citation style that I fixed. Originally, the first 4 references of the article were all citing the same article but each in a different format. Be sure to look over these things before submitting an article for GA review in the future.
There is not enough coverage of major aspects: How is this molecule synthesized? metabolized? The Fezza et al. 2002 paper cited in the article probably has information about its tissue distribution. This would be very relevant to know.
B. Focused:
The text is not very focus and not organized very well. There are too many irrelevant details about the method in the "Discovery" section. Replace this with information such as its discovery in places other than the brain and the dispute over its discovery. Also to be included in that section is not just about how they found the molecule, but how they found that the molecule was an endogenous ligand to CB1. Also, I would rename the "Production" section to "Physiologic functions" since it contains info about what the molecule does in the body. The pharmacology info in that section should be moved to the "Pharmacology" section.
A. Images are copyright tagged, and non-free images have fair use rationales:
B. Images are provided where possible and appropriate, with suitable captions:
Overall:
Pass or Fail:
I'm sorry to say that this article is not yet ready for GA status since there is still a lot of work to be done. But thank you for the work you have done on this article. If you intend to build on this article in the future, I would be happy to give you another peer review. I would love to see this article progress in the future.