Talk:2,6-Xylidine
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Inconsistant data on melting point.
[edit]This page has an mp of ~11.4. The generalized xylidine has an mp of 8.4 for the 2,6 isomer.
unsourced
[edit]moved here per WP:PRESERVE. Per WP:BURDEN please do not restore without finding reliable sources, checking the content against them, and citing them.
- Drug uses
2,6-Xylidine is used in the production of a slew of pharmaceutical drugs. For Example:
- Droxicainide
- Etidocaine
- Lidamidine
- Lidocaine (Lignocaine)
- Lidofenin
- Lidoflazine
- Nefiracetam
- Pincainide
- Ranolazine
- Tocainide
- Mepivacaine
- Bupivacaine
- Ropivacaine
A lot of these can be grouped as local anesthetics. The rationale behind using the ortho-dimethylated aniline design is to shield the molecule from enzymes that metabolize the drug by amide degradation.
-- Jytdog (talk) 20:37, 11 April 2017 (UTC)
unsourced 2
[edit]moved here per PRESERVE
- Drug uses
2,6-Xylidine is used in the production of some pharmaceutical drugs, including:[citation needed]
Many of these are local anesthetics. The rationale behind using the ortho-dimethylated aniline design is to shield the molecule from enzymes that metabolize the drug by amide degradation.