Jump to content

Talk:2,6-Xylidine

Page contents not supported in other languages.
From Wikipedia, the free encyclopedia

Inconsistant data on melting point.

[edit]

This page has an mp of ~11.4. The generalized xylidine has an mp of 8.4 for the 2,6 isomer.

unsourced

[edit]

moved here per WP:PRESERVE. Per WP:BURDEN please do not restore without finding reliable sources, checking the content against them, and citing them.

Drug uses

2,6-Xylidine is used in the production of a slew of pharmaceutical drugs. For Example:

  1. Droxicainide
  2. Etidocaine
  3. Lidamidine
  4. Lidocaine (Lignocaine)
  5. Lidofenin
  6. Lidoflazine
  7. Nefiracetam
  8. Pincainide
  9. Ranolazine
  10. Tocainide
  11. Mepivacaine
  12. Bupivacaine
  13. Ropivacaine

A lot of these can be grouped as local anesthetics. The rationale behind using the ortho-dimethylated aniline design is to shield the molecule from enzymes that metabolize the drug by amide degradation.

-- Jytdog (talk) 20:37, 11 April 2017 (UTC)[reply]

unsourced 2

[edit]

moved here per PRESERVE

Drug uses

2,6-Xylidine is used in the production of some pharmaceutical drugs, including:[citation needed]

Many of these are local anesthetics. The rationale behind using the ortho-dimethylated aniline design is to shield the molecule from enzymes that metabolize the drug by amide degradation.


-- Jytdog (talk) 02:32, 21 September 2017 (UTC)[reply]