Talk:1,2-Dibromo-3-chloropropane

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Untitled

The statement "No information is available on the chronic effects of DBCP in humans", while lifted directly from the quoted source is misleading, especially as the source lists several chronic exposure effects, e.g., "Chronic exposure to DBCP causes male reproductive effects". In particular, this page could benefit from discussion of the sterility claims of Costa Rican banana workers, especially in the period after DBCP was banned for use in the US but allowed to be transported to other countries.—The preceding unsigned comment was added by Mdwik (talk • contribs).

The article doesn't even mention its continued use in Central America after it was banned in the USA, http://www.inthesetimes.com/article/2096/

Metabolism and possible treatment

In rats a portion of the DBCP dose was shown to be excreted as mercapturic acids products. It is common for halogenated hydrocarbons to deplete the animal's cysteine stores, thereby inhibiting protein synthesis. Therefore, it would make sense to supplement the diet with cysteine, this should minimize the adverse effects on protein synthesis of DBCP and also help in the elimination of DBCP.

Sources: regarding the inhibition of growth (if protein intake is low) due to halogenated hydrocarbons, Biochemistry, eighth edition, authors Orten and Neuhaus, page 752-753. Regarding the metabolism of DBCP to mercapturic acids http://www.hendlerlaw.com/dbcppdf/TOXOLOGICAL%20PROFILE%20FOR%20DBCP.pdf 71.114.180.207 (talk) 02:25, 16 July 2010 (UTC)[reply]

Dead link

During several automated bot runs the following external link was found to be unavailable. Please check if the link is in fact down and fix or remove it in that case!

http://www.forbes.com/feeds/reuters/2009/04/24/2009-04-24T052809Z_01_N21503396_RTRIDST_0_BANANAS-UPDATE-2.html
- In Dow Chemical Company on 2011-03-17 15:30:36, 404 Not Found
- In 1,2-Dibromo-3-chloropropane on 2011-05-23 01:50:47, 404 Not Found
- In 1,2-Dibromo-3-chloropropane on 2011-05-31 15:26:02, 404 Not Found

--JeffGBot (talk) 15:26, 31 May 2011 (UTC)[reply]

Dead link 2

During several automated bot runs the following external link was found to be unavailable. Please check if the link is in fact down and fix or remove it in that case!

http://www.ca9.uscourts.gov/ca9/newopinions.nsf/40AB16BDDF8C33D9882574CD007E8677/$file/0756326.pdf?openelement
- In 1,2-Dibromo-3-chloropropane on 2011-05-23 01:50:54, 404 Not Found
- In 1,2-Dibromo-3-chloropropane on 2011-05-31 15:26:10, 404 Not Found

--JeffGBot (talk) 15:26, 31 May 2011 (UTC)[reply]