Talk:Α-Difluoromethyl-DOPA
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S- or racemic?
[edit]The chembox currently indicates the S-enanatiomer, with its structure, IUPAC name, and CAS number, but CAS (via SciFinder) associates all variations of the name "difluoromethyldopa" with the racemate (i.e. sterochemistry not indicated) and literature using these names fall under that CAS number as well, 69955-03-9, including the lone paper cited in the WP article. The CAS number was changed by Fswitzer4. I am inclined to follow CAS and change the CAS number back and either label the chembox structure as the S-enanatiomer, or replace it with a version without stereochemistry indicated. I would need to peruse the 20 or so papers to see if they focus on the one enantiomer. My guess is that this is synthesized as the racemic mixture but perhaps they've determined the S-enanatiomer is the active isomer. Thoughts?
- The stereochemistry makes sense I guess, given it's an analogue of L-DOPA. Anyway, if anyone who is more familiar with these compounds than me could weigh in, that'd be helpful. Mdewman6 (talk) 00:16, 4 May 2022 (UTC)