The TVB Anniversary Award for Most Popular Female Character is one of the TVB Anniversary Awards presented annually by Television Broadcasts Limited (TVB) to recognize an actress who has delivered a popular performance in a Hong Kong television drama role throughout the designated year. The My Favourite Female Television Role (我最喜愛的電視女角色) was not introduced to the awards ceremony until 2006, nine years after its establishment. In 2013, the name was changed to Most Popular Female Television Role (最受歡迎電視女角色).
The original equivalent of the award was called My Favourite Television Roles of the Year (本年度我最喜愛的電視角色), which was created in 2003. The award was given to 12 winners for both actors and actresses. In 2006, the award was divided into two separate gender categories and reduced to one specific winner. The 2019 awards ceremony was the first and only ceremony to have two winners tied for Most Popular Female Character.
TVB nominates at least ten actresses for the category each year. The following table lists only the actresses who have made it to the top five nominations during the designated awards ceremony. There were no top five nominations from 2012 to 2014.