TRANK1

TRANK1
Identifiers
Aliases	TRANK1, LBA1, tetratricopeptide repeat and ankyrin repeat containing 1
External IDs	MGI: 1341834; HomoloGene: 45845; GeneCards: TRANK1; OMA:TRANK1 - orthologs
Gene location (Human) Chr. Chromosome 3 (human) Band 3p22.2 Start 36,826,819 bp End 36,945,057 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band 9|9 F3 Start 111,140,807 bp End 111,224,843 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum left uterine tube jejunal mucosa body of uterus right uterine tube canal of the cervix blood Descending thoracic aorta granulocyte rectum Top expressed in superior frontal gyrus primary visual cortex adrenal cortex olfactory tubercle lumbar subsegment of spinal cord dentate gyrus of hippocampal formation granule cell nucleus accumbens piriform cortex nucleus of stria terminalis frenulum of tongue More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 9881 320429 Ensembl ENSG00000168016 ENSMUSG00000062296 UniProt O15050 Q8BV79 RefSeq (mRNA) NM_014831 NM_001329998 NM_001164659 RefSeq (protein) NP_001316927 NP_055646 NP_001158131 Location (UCSC) Chr 3: 36.83 – 36.95 Mb Chr 9: 111.14 – 111.22 Mb PubMed search
Wikidata
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Tetratricopeptide repeat and ankyrin repeat containing 1 is a protein that in humans is encoded by the TRANK1 gene.

Disease Linkage

Through a Genome-wide association study, TRANK1 has been relationed with the Bipolar disorder.

Further reading

• Goes FS, Hamshere ML, Seifuddin F, Pirooznia M, Belmonte-Mahon P, Breuer R, et al. (October 2012). "Genome-wide association of mood-incongruent psychotic bipolar disorder". Translational Psychiatry. 2 (10): e180. doi:10.1038/tp.2012.106. PMC 3565814. PMID 23092984.
• Chen DT, Jiang X, Akula N, Shugart YY, Wendland JR, Steele CJ, et al. (February 2013). "Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder". Molecular Psychiatry. 18 (2): 195–205. doi:10.1038/mp.2011.157. PMID 22182935.