TC2N

TC2N
Identifiers
Aliases	TC2N, C14orf47, C2CD1, MTAC2D1, Tac2-N, tandem C2 domains, nuclear, TAC2N
External IDs	MGI: 1921663; HomoloGene: 12560; GeneCards: TC2N; OMA:TC2N - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	91,867,536 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	101,684,782 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; tonsil; ; olfactory zone of nasal mucosa; ; gallbladder; ; Descending thoracic aorta; ; ascending aorta; ; islet of Langerhans; ; epithelium of colon; ; salivary gland; ; minor salivary glands;
	Top expressed in
	seminal vesicula; ; parotid gland; ; lacrimal gland; ; epithelium of stomach; ; retinal pigment epithelium; ; Epithelium of choroid plexus; ; submandibular gland; ; transitional epithelium of urinary bladder; ; left lung lobe; ; olfactory epithelium;
	More reference expression data
	n/a
Gene ontology
Molecular function	clathrin binding; calcium ion binding; syntaxin binding; molecular function; calcium-dependent phospholipid binding;
Cellular component	nucleus; plasma membrane; cellular component; synapse; presynapse;
Biological process	vesicle fusion; calcium ion-regulated exocytosis of neurotransmitter; regulation of calcium ion-dependent exocytosis;
	Sources:Amigo / QuickGO
Orthologs
	123036
	74413
	ENSG00000276776; ENSG00000165929
	ENSMUSG00000021187
	Q8N9U0
	Q91XT6
	NM_152332; NM_001128595; NM_001128596; NM_001289134
	NM_001082976; NM_001286364; NM_028924
	NP_001122067; NP_001122068; NP_001276063; NP_689545
	NP_001076445; NP_083200
	Wikidata
View/Edit Human	View/Edit Mouse

Tandem C2 domains nuclear protein is a protein that in humans is encoded by the TC2N gene.^[5]^[6]

References

^ ^a ^b ^c ENSG00000165929 GRCh38: Ensembl release 89: ENSG00000276776, ENSG00000165929 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021187 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Fukuda M, Mikoshiba K (Aug 2001). "Tac2-N, an atypical C-type tandem C2 protein localized in the nucleus". FEBS Lett. 503 (2–3): 217–218. doi:10.1016/S0014-5793(01)02738-7. PMID 11526914. S2CID 33045301.
^ "Entrez Gene: MTAC2D1 membrane targeting (tandem) C2 domain containing 1".

Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–D418. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–2144. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–435. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–1795. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.

This article on a gene on human chromosome 14 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] ENSG00000165929 GRCh38: Ensembl release 89: ENSG00000276776, ENSG00000165929 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021187 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11526914-5] Fukuda M, Mikoshiba K (Aug 2001). "Tac2-N, an atypical C-type tandem C2 protein localized in the nucleus". FEBS Lett. 503 (2–3): 217–218. doi:10.1016/S0014-5793(01)02738-7. PMID 11526914. S2CID 33045301.

[entrez-6] "Entrez Gene: MTAC2D1 membrane targeting (tandem) C2 domain containing 1".

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References

Further reading